Procreation is essential for survival of species. Not surprisingly, complex neuronal networks
have evolved to mediate the diverse internal and external environmental inputs that regulate …

This review aims at synthesizing the most relevant information regarding the
neuroendocrine circuits controlling reproduction, mainly gonadotropin release, in teleost …

Kisspeptin (a product of the Kiss1 gene) and its receptor (GPR54 or Kiss1r) have emerged
as key players in the regulation of reproduction. Mutations in humans or genetically targeted …

Puberty comprises the transition from an immature juvenile to a mature adult state of the
reproductive system, ie the individual becomes capable of reproducing sexually for the first …

Teleosts lack a hypophyseal portal system and hence neurohormones are carried by nerve
fibers from the preoptic region to the pituitary. The various cell types in the teleost pituitary …

Newly discovered kisspeptin (metastin), encoded by the Kiss1/KISS1 gene, is considered as
a major gatekeeper of puberty through the regulation of GnRH. In the present study, we …

The kiss1/gpr54 signaling system is considered to be a critical regulator of reproduction in
most vertebrates. However, this presumption has not been tested vigorously in …

Kisspeptins are new actors in the neuroendocrine regulation of reproduction. In vertebrates,
the number of kiss genes varies from none to three. Zebrafish have two kiss genes, kiss1 …

Kisspeptins, the products of KiSS-1 gene, have recently emerged as fundamental regulators
of reproductive function in different mammalian and, presumably, non-mammalian species …

BACKGROUND Kisspeptins, and their cognate receptor gpr-54, were first found to regulate
the hypothalamic–pituitary–gonadal (HPG) axis in 2003, when two groups demonstrated …