[HTML][HTML] The pathophysiology of gestational diabetes mellitus

JF Plows, JL Stanley, PN Baker, CM Reynolds… - International journal of …, 2018 - mdpi.com
Gestational diabetes mellitus (GDM) is a serious pregnancy complication, in which women
without previously diagnosed diabetes develop chronic hyperglycemia during gestation. In …

[HTML][HTML] IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Gestational diabetes mellitus: an updated overview

E Chiefari, B Arcidiacono, D Foti, A Brunetti - Journal of endocrinological …, 2017 - Springer
The clinical and public health relevance of gestational diabetes mellitus (GDM) is widely
debated due to its increasing incidence, the resulting negative economic impact, and the …

[HTML][HTML] Host remodeling of the gut microbiome and metabolic changes during pregnancy

O Koren, JK Goodrich, TC Cullender, A Spor… - Cell, 2012 - cell.com
Many of the immune and metabolic changes occurring during normal pregnancy also
describe metabolic syndrome. Gut microbiota can cause symptoms of metabolic syndrome …

[HTML][HTML] Fetal programming and cardiovascular pathology

BT Alexander, JH Dasinger… - Comprehensive Physiology, 2015 - ncbi.nlm.nih.gov
Low birth weight serves as a crude proxy for impaired growth during fetal life and indicates a
failure for the fetus to achieve its full growth potential. Low birth weight can occur in …

Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews

R Martis, CA Crowther, E Shepherd… - Cochrane Database …, 2018 - cochranelibrary.com
Background Successful treatments for gestational diabetes mellitus (GDM) have the
potential to improve health outcomes for women with GDM and their babies. Objectives To …

Microbiome and its relation to gestational diabetes

RV Cortez, CR Taddei, LG Sparvoli, AGS Ângelo… - Endocrine, 2019 - Springer
Purpose Gestational diabetes mellitus (GDM), the major endocrine pathology in pregnancy,
has been associated with the development of an intense inflammatory process and …

Genetic variants and the risk of gestational diabetes mellitus: a systematic review

C Zhang, W Bao, Y Rong, H Yang… - Human reproduction …, 2013 - academic.oup.com
BACKGROUND Several studies have examined associations between genetic variants and
the risk of gestational diabetes mellitus (GDM). However, inferences from these studies were …

New insights into gestational glucose metabolism: lessons learned from 21st century approaches

AR Angueira, AE Ludvik, TE Reddy, B Wicksteed… - Diabetes, 2015 - Am Diabetes Assoc
Pregnancy presents a unique physiological challenge that requires changes coordinated by
placentally and non–placentally derived hormones to prepare the mother for the metabolic …

Adverse pregnancy outcomes and long-term maternal kidney disease: a systematic review and meta-analysis

PM Barrett, FP McCarthy, K Kublickiene… - JAMA network …, 2020 - jamanetwork.com
Importance Adverse pregnancy outcomes, such as hypertensive disorders of pregnancy,
gestational diabetes, and preterm delivery, are associated with increased risk of maternal …