Polymorphism of human cytochrome P450 enzymes and its clinical impact

SF Zhou, JP Liu, B Chowbay - Drug metabolism reviews, 2009 - Taylor & Francis
Pharmacogenetics is the study of how interindividual variations in the DNA sequence of
specific genes affect drug response. This article highlights current pharmacogenetic …

[HTML][HTML] Fungal endophthalmitis: a comprehensive review

AA Haseeb, AM Elhusseiny, MZ Siddiqui, KT Ahmad… - Journal of Fungi, 2021 - mdpi.com
Endophthalmitis is a serious ophthalmologic condition involving purulent inflammation of the
intraocular spaces. The underlying etiology of infectious endophthalmitis is typically …

Antifungal activity of silver nanoparticles against Candida spp.

A Panáček, M Kolář, R Večeřová, R Prucek… - Biomaterials, 2009 - Elsevier
The antifungal activity of the silver nanoparticles (NPs) prepared by the modified Tollens
process was evaluated for pathogenic Candida spp. by means of the determination of the …

The effect of therapeutic drug monitoring on safety and efficacy of voriconazole in invasive fungal infections: a randomized controlled trial

WB Park, NH Kim, KH Kim, SH Lee… - Clinical Infectious …, 2012 - academic.oup.com
Background. Blood levels of voriconazole, a first line therapy for invasive aspergillosis, may
correlate with adverse events and treatment response. However, no randomized controlled …

Clinical hepatotoxicity associated with antifungal agents

I Kyriakidis, A Tragiannidis, S Munchen… - Expert opinion on drug …, 2017 - Taylor & Francis
ABSTRACT Introduction: Invasive fungal diseases (IFDs) are a leading cause of morbidity
and mortality among immunocompromised patients with bone marrow failure syndromes …

Pharmacogenetics: from bench to byte

JJ Swen, I Wilting, AL De Goede… - Clinical …, 2008 - Wiley Online Library
Despite initial enthusiasm, 1, 2, 3 the use of pharmacogenetics has remained limited to
investigation in only a few clinical fields such as oncology and psychiatry. 4, 5, 6, 7, 8 The …

Synthesis of magnetic nanoparticles and their dispersions with special reference to applications in biomedicine and biotechnology

RV Mehta - Materials Science and Engineering: C, 2017 - Elsevier
Biomedical and biotechnological applications of magnetic nanoparticles and their
dispersions in liquids are found to be potentially useful. An exponential growth in …

Effect of a denture base acrylic resin containing silver nanoparticles on Candida albicans adhesion and biofilm formation

Z Li, J Sun, J Lan, Q Qi - Gerodontology, 2016 - Wiley Online Library
Objective The objective of this study was to evaluate the effect of denture base resin
containing silver nanoparticles (nano‐silver) on Candida albicans adhesion and biofilm …

Systematic review and meta-analysis of the tolerability and hepatotoxicity of antifungals in empirical and definitive therapy for invasive fungal infection

JL Wang, CH Chang, Y Young-Xu… - Antimicrobial agents and …, 2010 - Am Soc Microbiol
To evaluate the tolerability and liver safety profiles of the systemic antifungal agents
commonly used for the treatment of invasive fungal infection, we conducted a systematic …

CYP2C19 Polymorphisms and Therapeutic Drug Monitoring of Voriconazole: Are We Ready for Clinical Implementation of Pharmacogenomics?

A Owusu Obeng, EF Egelund, A Alsultan… - … : The Journal of …, 2014 - Wiley Online Library
Since its approval by the US Food and Drug Administration in 2002, voriconazole has
become a key component in the successful treatment of many invasive fungal infections …