Heart failure (HF) describes a heterogenous complex spectrum of pathological conditions
that results in structural and functional remodeling leading to subsequent impairment of …

Aims While global longitudinal strain (GLS) is considered to be a sensitive marker of left
ventricular (LV) function, it is significantly influenced by loading conditions. We hypothesized …

Abstract Aims Interleukin-1β (IL-1β) is an important pathogenic factor in cardiovascular
diseases including chronic heart failure (HF). The CANTOS trial highlighted that …

Aims: Pathological left ventricular (LV) remodeling induced by multiple causes often triggers
fatal cardiac dysfunction, heart failure (HF), and even cardiac death. This study is aimed to …

The identification of novel drug targets is needed to improve the outcomes of heart failure
(HF). G-protein-coupled receptors (GPCRs) represent the largest family of targets for already …

The constant and dynamic interaction between ventricular function and arterial afterload,
known as ventricular-arterial coupling, is key to understanding cardiovascular …

In patients with heart failure and functional mitral regurgitation (FMR), the assessment of left
ventricular (LV) function is important for risk stratification and decision making. As LV …

Objective This study aimed to demonstrate the reliability of the cardiac cycle efficiency value
through its correlation with longitudinal strain by observing the effect of the deep …

Heart failure with reduced ejection fraction (HFrEF) exhibits exaggerated sympathoexcitation
and altered cardiac and vascular responses to muscle metaboreflex activation (MMA) …

Object Aortic stenosis and regurgitation are clinically important conditions characterized with
different hypertrophic types induced by pressure or volume overload, respectively, but with …