The human preterm brain is particularly susceptible to cerebral white matter injury (WMI) that
disrupts the normal progression of developmental myelination. Advances in the care of …

Prematurity, especially preterm birth (less than 32 weeks' gestation), is common and
associated with high rates of both survival and neurodevelopmental disability, especially …

With advances in neonatal care, preterm neonates are surviving with an evolving
constellation of motor and cognitive disabilities that appear to be related to widespread …

With a worldwide incidence of 15 million cases, preterm birth is a major contributor to
neonatal mortality and morbidity, and concomitant social and economic burden Preterm …

Perinatal brain injury (PBI) in preterm birth is associated with substantial injury and
dysmaturation of white and gray matter, and can lead to severe neurodevelopmental deficits …

Children surviving preterm birth have a high risk of disability, particularly cognitive and
learning problems. There is extensive clinical and experimental evidence that disability is …

Cerebral palsy (CP) is a complex multifactorial disorder, affecting approximately 2.5–3/1000
live term births, and up to 22/1000 prematurely born babies. CP results from injury to the …

Injury to the preterm brain has a particular predilection for cerebral white matter. White
matter injury (WMI) is the most common cause of brain injury in preterm infants and a major …

Objective: To quantitatively assess white matter injury (WMI) volume and location in very
preterm neonates, and to examine the association of lesion volume and location with 18 …

Despite the advances in neonatal intensive care, the preterm brain remains vulnerable to
white matter injury (WMI) and disruption of normal brain development (ie, dysmaturation) …