Simple Summary This review describes in a very detailed and exhaustive approach the
literature of these last 20 years on glioblastoma targeted therapies in Phases II-IV of 257 …

Glioblastoma multiforme (GBM) represents the most malignant primary brain tumor in adults
with generally dismal prognosis, early clinical deterioration and high mortality. GBM is …

Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and
mortality. Heme oxygenase-1 (HO-1), the key enzyme in heme degradation, is highly …

Cancer is one of the diseases with the highest morbidity and mortality rates worldwide, and
its therapeutic options are inadequate. The endothelial glycoprotein, also known as CD105 …

Introduction Glioblastoma (GBM) is notorious for its clinical and molecular heterogeneity,
contributing to therapeutic failure and a grim prognosis. WWOX is one of the tumor …

Glioblastoma (GBM) is an aggressive central nervous system cancer with poor prognosis
despite maximal therapy. The recent advent of immunotherapy holds great promise for …

Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a poor
prognosis for which no effective therapeutic measures are currently available. The present …

Gestational trophoblastic neoplasia (GTN) is a rare pregnancy-related gynecological
malignancy caused by abnormal proliferation of placental trophoblastic cells. It can invade …

Introduction CD105 is an angiogenic biomarker that is useful to determine the microvessel
density (MVD) within a tumor, namely, in highly vascularized tumors like glioblastoma …

Glioblastoma (GBM) is the most common and deadly malignant brain tumor, with a median
survival of 15 to 17 months for a patient. GBM contains a cellular subpopulation known as …