Cholesterol plays critical functions in arranging the biophysical attributes of proteins and
lipids in the plasma membrane. For various viruses, an association with cholesterol for virus …

Cholesterol is an essential component of mammalian cell membranes and a precursor for
crucial signaling molecules. The brain contains the highest level of cholesterol in the body …

Abstract Recently, COVID-19, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) and its variants, caused> 6 million deaths. Symptoms included respiratory …

A new series of heterocyclic derivatives with a 1, 7, 7‐trimethylbicyclo [2.2. 1] heptane
fragment was designed, synthesised and biologically evaluated. Synthesis of the target …

We broaden the clinical versatility of human nasal epithelial (HNE) cells. HNEs were
isolated from 10 participants harboring cystic fibrosis transmembrane conductance regulator …

Immunostaining in lungs of patients who died with COVID-19 infection showed increased
intensity and distribution of chondroitin sulfate and decline in N-acetylgalactostamine-4 …

Atopic dermatitis (AD) is a common inflammatory skin disease, in particular among infants,
and is characterized, among other things, by a modification in fatty acid and ceramide …

Illuminated by insights into the hijacking of host cellular metabolism by coronaviruses, we
identified an initial hit compound 7030B-C5, characterized by a xanthine scaffold, via a …

Background: Multiple biologics have been recently suggested as a new treatment for chronic
rhinosinusitis with nasal polyps (CRSwNP). Currently, only two drugs can be prescribed in …