Cell membrane-derived nanomaterials for biomedical applications

RH Fang, Y Jiang, JC Fang, L Zhang - Biomaterials, 2017 - Elsevier
The continued evolution of biomedical nanotechnology has enabled clinicians to better
detect, prevent, manage, and treat human disease. In order to further push the limits of …

Mechanical force-triggered drug delivery

Y Zhang, J Yu, HN Bomba, Y Zhu, Z Gu - Chemical reviews, 2016 - ACS Publications
Advanced drug delivery systems (DDS) enhance treatment efficacy of different therapeutics
in a dosage, spatial, and/or temporal controlled manner. To date, numerous chemical-or …

Biomimetic nanoparticle technology for cardiovascular disease detection and treatment

JH Park, D Dehaini, J Zhou, M Holay, RH Fang… - Nanoscale …, 2020 - pubs.rsc.org
Cardiovascular disease (CVD), which encompasses a number of conditions that can affect
the heart and blood vessels, presents a major challenge for modern-day healthcare. Nearly …

The influence of size, shape and vessel geometry on nanoparticle distribution

J Tan, S Shah, A Thomas, HD Ou-Yang… - Microfluidics and …, 2013 - Springer
Nanoparticles (NPs) are emerging as promising carrier platforms for targeted drug delivery
and imaging probes. To evaluate the delivery efficiency, it is important to predict the …

[HTML][HTML] Targeted chemotherapy via HER2-based chimeric antigen receptor (CAR) engineered T-cell membrane coated polymeric nanoparticles

S Yaman, H Ramachandramoorthy, P Iyer… - Bioactive Materials, 2024 - Elsevier
Cell membrane-derived nanoparticles (NPs) have recently gained popularity due to their
desirable features in drug delivery such as mimicking properties of native cells, impeding …

Platelets and their biomimetics for regenerative medicine and cancer therapies

Z Li, S Hu, K Cheng - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
Platelets, circulating blood cells derived from megakaryocytes, play a key role in various
physical activities, including coagulation, hemostasis, the body's innate immune response …

Platelet-mimicking drug delivery nanoparticles for enhanced chemo-photothermal therapy of breast cancer

W Pei, B Huang, S Chen, L Wang, Y Xu… - International Journal of …, 2020 - Taylor & Francis
Background Traditional nanoparticle-based drug delivery systems suffer from several
limitations, such as easy clearance from blood and inaccurate targeting. Materials and …

Engineering and evaluating drug delivery particles in microfluidic devices

M Björnmalm, Y Yan, F Caruso - Journal of Controlled Release, 2014 - Elsevier
The development of new and improved particle-based drug delivery is underpinned by an
enhanced ability to engineer particles with high fidelity and integrity, as well as increased …

Nanoparticles and the blood coagulation system. Part I: benefits of nanotechnology

AN Ilinskaya, MA Dobrovolskaia - Nanomedicine, 2013 - Taylor & Francis
Nanotechnology is proven to provide certain benefits in drug delivery by improving solubility,
increasing uptake to target sites and changing pharmacokinetics profiles of traditional drugs …

Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells

J Cui, L Qin, J Zhang, P Abrahimi, H Li, G Li… - Nature …, 2017 - nature.com
Human endothelial cells are initiators and targets of the rejection response. Pre-operative
modification of endothelial cells by small interfering RNA transfection could shape the nature …