Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

Skeletal muscle health is a strong predictor of overall health and longevity. Pathologies
affecting skeletal muscle such as cancer cachexia, intensive care unit treatment, muscular …

Satellite cells support adult skeletal muscle fiber adaptations to loading in numerous ways.
The fusion of satellite cells, driven by cell‐autonomous and/or extrinsic factors, contributes …

Skeletal muscle hypertrophy can be induced by hormones and growth factors acting directly
as positive regulators of muscle growth or indirectly by neutralizing negative regulators, and …

Science and Development of Muscle Hypertrophy, Second Edition, is the most
comprehensive resource on muscle hypertrophy in the world. Written by Brad Schoenfeld …

The maintenance of skeletal muscle mass plays a critical role in health and quality of life.
One of the most potent regulators of skeletal muscle mass is mechanical loading, and …

The ribosome is the enzymatic macromolecular machine responsible for protein synthesis.
The rates of protein synthesis are primarily dependent on translational efficiency and …

It is well known that an increase in mechanical loading can induce skeletal muscle
hypertrophy, and a long standing model in the field indicates that mechanical loads induce …

Sarcopenia has been defined as a progressive decline of skeletal muscle mass, strength,
and functions in elderly people. It is accompanied by physical frailty, functional disability …