Sleep is an important modulator of neuroendocrine function and glucose metabolism and
sleep loss has been shown to result in metabolic and endocrine alterations, including …

Experimental approaches directed at addressing these issues are limited by several
considerations. First, the close association between obesity and OSA often obscures …

Rationale: Randomized controlled trials have been unable to detect a cardiovascular benefit
of continuous positive airway pressure in unselected patients with obstructive sleep apnea …

Description: The American College of Physicians (ACP) developed this guideline to present
the evidence and provide clinical recommendations on the diagnosis of obstructive sleep …

Rationale: Sleep-disordered breathing (SDB) has been associated with total and
cardiovascular mortality, but an association with cancer mortality has not been studied …

Importance Based on data from the 1990s, estimated prevalence of obstructive sleep apnea
(OSA) in the United States is 10% for mild OSA and 3.8% to 6.5% for moderate to severe …

The purpose of this review is to conduct a systematic review and meta-analysis comparing
the effects of continuous positive airway pressure (CPAP) with a mandibular advancement …

Excess weight is a well-established predictor of sleep-disordered breathing (SDB). Clinical
observations and population studies throughout the United States, Europe, Asia, and …

OSA is a heterogeneous disease with highly varying underlying mechanisms. OSA has
variable clinical manifestations with definable subsets having risk of particular …

Percutaneous renal sympathetic denervation by radiofrequency energy has been reported
to reduce blood pressure (BP) by the reduction of renal sympathetic efferent and afferent …