The efficacy of an antiretroviral (ARV) treatment regimen depends on the activity of the
regimen's individual ARV drugs and the number of HIV-1 mutations required for the …

Whole genome sequencing (WGS) promises to be transformative for the practice of clinical
microbiology, and the rapidly falling cost and turnaround time mean that this will become a …

Despite scientific evidence originating from two patients published to date that
CCR5Δ32/Δ32 hematopoietic stem cell transplantation (HSCT) can cure human …

Background Contemporary antiretroviral therapies (ART) and management strategies have
diminished both human immunodeficiency virus (HIV) treatment failure and the acquired …

Novel DNA sequencing techniques, referred to as “next-generation” sequencing (NGS),
provide high speed and throughput that can produce an enormous volume of sequences …

Many viruses, including the clinically relevant RNA viruses HIV (human immunodeficiency
virus) and HCV (hepatitis C virus), exist in large populations and display high genetic …

Next-generation sequencing (NGS) technologies are increasingly being used for diagnosis
and monitoring of infectious diseases. Herein, we review the application of NGS in clinical …

Access to combination antiretroviral treatment (ART) has improved greatly over recent years.
At the end of 2011, more than eight million HIV-infected people were receiving ART in low …

Next-generation sequencing allows for cost-effective probing of virus populations at an
unprecedented level of detail. The massively parallel sequencing approach can detect low …

Recent advances in nucleic acid sequencing technologies, referred to as 'next-generation'
sequencing (NGS), have produced a true revolution and opened new perspectives for …