A Histomorphometric and computational investigation of the stabilizing role of pectinate ligaments in the aqueous outflow pathway

BN Safa, NS Fraticelli Guzmán… - Journal of …, 2024 - asmedigitalcollection.asme.org
Murine models are commonly used to study glaucoma, the leading cause of irreversible
blindness. Glaucoma is associated with elevated intra-ocular pressure (IOP), which is …

Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived from Clinical and Human Iris Data

RKY Tan, TA Tun, FA Braeu, SA Perera, MJA Girard - bioRxiv, 2025 - biorxiv.org
Purpose: To investigate the effect of crypts during pupil constriction and dilation on the
potential for angle closure by performing finite element analysis using clinical and …

The Structural Layers of the Porcine Iris Exhibit Inherently Different Biomechanical Properties

RKY Tan, SK Panda, FA Braeu… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: The purpose of this study was to isolate the structural components of the ex vivo
porcine iris tissue and to determine their biomechanical properties. Methods: The porcine …

Characterizing regional biomechanical properties of the porcine iris using optical coherence elastography

T Mekonnen, C Zevallos-Delgado… - Optical …, 2023 - spiedigitallibrary.org
The fundamental physiological function of the iris is to control the amount of light entering
the eye, which requires the coordinated constriction or dilation of the pupil, affected by two …