Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …

Vaccination was first pioneered in the 18th century by Edward Jenner and eventually led to
the development of the smallpox vaccine and subsequently the eradication of smallpox. The …

The development of therapeutic cancer vaccines as a means to generate immune reactivity
against tumors has been explored since the early discovery of tumor-specific antigens by …

Accumulating evidence indicates that microRNA-146a (miR-146a), a well-known anti-
inflammatory miRNA, acts as a negative feedback regulator of the innate immune response …

Cancer progression is marked by the infiltration of immunosuppressive cells, such as tumor-
associated macrophages (TAMs), regulatory T lymphocytes (Tregs), and myeloid-derived …

Oxymatrine (OMT) is an important quinoxaline alkaloid that has a wide range of
pharmacological effects and has been shown to alleviate ulcerative colitis due to its …

Vasoactive intestinal peptide (VIP) is a neuropeptide that exerts anti-inflammatory functions.
We have reported that VIP mediated by lentivirus attenuates acute lung injury (ALI) in …

Landmark successes in oncoimmunology have led to development of therapeutics boosting
the host immune system to eradicate local and distant tumors with impactful tumor reduction …

Traditional vaccines such as live-attenuated or whole-killed vaccines have been widely
used over the past hundred years. However, the safety and effectiveness of traditional …

Vertebral compression fractures are a very common consequence of osteoporosis for which
injection of a non-biodegradable, non-bioactive, mechanically-stiff polymer bone cement …