Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?
B Halliwell, M Whiteman - British journal of pharmacology, 2004 - Wiley Online Library
Free radicals and other reactive species (RS) are thought to play an important role in many
human diseases. Establishing their precise role requires the ability to measure them and the …
human diseases. Establishing their precise role requires the ability to measure them and the …
Oxidatively induced DNA damage and its repair in cancer
M Dizdaroglu - Mutation Research/Reviews in Mutation Research, 2015 - Elsevier
Oxidatively induced DNA damage is caused in living organisms by endogenous and
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …
Oxidatively induced DNA damage: mechanisms, repair and disease
M Dizdaroglu - Cancer letters, 2012 - Elsevier
Endogenous and exogenous sources cause oxidatively induced DNA damage in living
organisms by a variety of mechanisms. The resulting DNA lesions are mutagenic and …
organisms by a variety of mechanisms. The resulting DNA lesions are mutagenic and …
Urinary biomarkers of oxidative status
D Il'yasova, P Scarbrough, I Spasojevic - Clinica chimica acta, 2012 - Elsevier
Oxidative damage produced by reactive oxygen species (ROS) has been implicated in the
etiology and pathology of many health conditions, including a large number of chronic …
etiology and pathology of many health conditions, including a large number of chronic …
[HTML][HTML] Biomarkers of nucleic acid oxidation–A summary state-of-the-art
Oxidatively generated damage to DNA has been implicated in the pathogenesis of a wide
variety of diseases. Increasingly, interest is also focusing upon the effects of damage to the …
variety of diseases. Increasingly, interest is also focusing upon the effects of damage to the …
Urinary 8-hydroxydeoxyguanosine and its analogs as DNA marker of oxidative stress: development of an ELISA and measurement in both bladder and prostate …
CC Chiou, PY Chang, EC Chan, TL Wu, KC Tsao… - Clinica chimica acta, 2003 - Elsevier
Background: 8-hydroxydeoxyguanosine (8-OHdG) is the most frequently detected and
studied DNA lesion. Upon DNA repair, 8-OHdG is excreted in the urine. Urinary 8-OHdG is …
studied DNA lesion. Upon DNA repair, 8-OHdG is excreted in the urine. Urinary 8-OHdG is …
[PDF][PDF] Biomarkers
The earliest work on oxidation of a biologically important protein was on the effects of
selected radicals generated by radiolysis on the enzyme, lysozyme (Adams et al., 1969) …
selected radicals generated by radiolysis on the enzyme, lysozyme (Adams et al., 1969) …
Oxidative DNA damage: assessment of the role in carcinogenesis, atherosclerosis, and acquired immunodeficiency syndrome
Free radical attack upon DNA generates a multiplicity of DNA damage, including modified
bases. Some of these modifications have considerable potential to damage the integrity of …
bases. Some of these modifications have considerable potential to damage the integrity of …
Effect of diet on cancer development: is oxidative DNA damage a biomarker?
B Halliwell - Free Radical Biology and Medicine, 2002 - Elsevier
Free radicals and other reactive species are generated in vivo and many of them can cause
oxidative damage to DNA. Although there are methodological uncertainties about accurate …
oxidative damage to DNA. Although there are methodological uncertainties about accurate …
Measurement and meaning of oxidatively modified DNA lesions in urine
Background: Oxidatively generated damage to DNA has been implicated in the
pathogenesis of a wide variety of diseases. The noninvasive assessment of such damage …
pathogenesis of a wide variety of diseases. The noninvasive assessment of such damage …