This article summarizes the likely benefits of melatonin in the attenuation of COVID-19
based on its putative pathogenesis. The recent outbreak of COVID-19 has become a …

Exogenous melatonin has been investigated as treatment for a number of medical and
surgical diseases, demonstrating encouraging results. The aim of this review was to present …

Melatonin modulates a wide range of physiological functions with pleiotropic effects on the
immune system. Despite the large number of reports implicating melatonin as an …

Antioxidant enzymes form the first line of defense against free radicals in organisms. Their
regulation depends mainly on the oxidant status of the cell, given that oxidants are their …

Pro-inflammatory systemic conditions that can cause neuroinflammation and subsequent
alterations in brain regions involved in emotional regulation have been suggested as an …

Objective: Melatonin has been shown to be neuroprotective in animal models. The objective
of this study is to examine the effect of melatonin on clinical, biochemical …

This brief resume enumerates the multiple actions of melatonin as an antioxidant. This
indoleamine is produced in the vertebrate pineal gland, the retina and possibly some other …

Chronic inflammation contributes to multiple diseases including cardiovascular diseases,
autoimmune disorders, metabolic disorders, and psychiatric conditions. Melatonin, a …

Intrapartum-related events are the third leading cause of childhood mortality worldwide and
result in one million neurodisabled survivors each year. Infants exposed to a perinatal insult …

The discovery of melatonin and its derivatives as antioxidants has stimulated a very large
number of studies which have, virtually uniformly, documented the ability of these molecules …