The use of RNA-based treatments in the field of cancer immunotherapy

M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Scalable production of extracellular vesicles and its therapeutic values: a review

CY Ng, LT Kee, ME Al-Masawa, QH Lee… - International Journal of …, 2022 - mdpi.com
Extracellular vesicles (EVs) are minute vesicles with lipid bilayer membranes. EVs are
secreted by cells for intercellular communication. Recently, EVs have received much …

Role of galectin 3 binding protein in cancer progression: a potential novel therapeutic target

E Capone, S Iacobelli, G Sala - Journal of translational medicine, 2021 - Springer
The lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a secreted,
hyperglycosylated protein expressed by the majority of human cells. It was first identified as …

Extracellular vesicle–based drug delivery in cancer immunotherapy

S Najafi, J Majidpoor, K Mortezaee - Drug Delivery and Translational …, 2023 - Springer
Extracellular vesicles (EVs) are a group of nanoscale membrane-bound organelles
including exosomes, microvesicles (MVs), membrane particles, and apoptotic bodies, which …

Harnessing engineered immune cells and bacteria as drug carriers for cancer immunotherapy

J Jiang, Y Huang, Z Zeng, C Zhao - ACS nano, 2023 - ACS Publications
Immunotherapy continues to be in the spotlight of oncology therapy research in the past few
years and has been proven to be a promising option to modulate one's innate and adaptive …

Cancer stem cells and the tumor microenvironment: targeting the critical crosstalk through nanocarrier systems

A Nayak, NM Warrier, P Kumar - Stem cell reviews and reports, 2022 - Springer
The physiological state of the tumor microenvironment (TME) plays a central role in cancer
development due to multiple universal features that transcend heterogeneity and niche …

Exosome-based cancer vaccine: A cutting-edge approach–Correspondence

R Dhar, B Bhattacharya, D Mandal… - … journal of surgery, 2022 - journals.lww.com
Exosomes are the subpopulation of extracellular vesicles (EVs). It originated from, plasma
membrane and involved in cellular communication. EVs transport several biologically active …

[HTML][HTML] Exosomes: Insights and therapeutic applications in cancer

AR Panigrahi, L Srinivas, J Panda - Translational Oncology, 2022 - Elsevier
Cancer refers to the division of abnormal cells at an uncontrollable rate that possesses the
ability to infiltrate and destroy normal tissues. It frequently spreads to normal tissues …

Extracellular vesicles and their roles in the tumor immune microenvironment

A Reale, T Khong, A Spencer - Journal of Clinical Medicine, 2022 - mdpi.com
Tumor cells actively incorporate molecules (eg, proteins, lipids, RNA) into particles named
extracellular vesicles (EVs). Several groups have demonstrated that EVs can be transferred …

Extracellular vesicles: a novel tool in nanomedicine and cancer treatment

A Stavrou, A Ortiz - Cancers, 2022 - mdpi.com
Simple Summary Extracellular vesicles (EVs) are plasma-membrane-encased particles with
various biomolecules. Recent studies have demonstrated that EVs play a role in …