Designing drugs when there is low data availability: one-shot learning and other approaches to face the issues of a long-term concern
GC Verissimo, MSM Serafim… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Modern drug discovery is generally accessed by useful information from
previous large databases or uncovering novel data. The lack of biological and/or chemical …
previous large databases or uncovering novel data. The lack of biological and/or chemical …
[HTML][HTML] Navigating the GSK-3β inhibitors as versatile multi-target drug ligands in Alzheimer's disease intervention–A comprehensive review
NJ Joshi, ARS Reddy - Results in Chemistry, 2024 - Elsevier
Alzheimer's disease (AD) remains a significant global health challenge, necessitating the
exploration of novel therapeutic strategies. AD is a neurodegenerative disease …
exploration of novel therapeutic strategies. AD is a neurodegenerative disease …
In silico strategies for probing novel DPP-IV inhibitors as anti-diabetic agents
S Sharma, S Srivastav, G Singh, S Singh… - Journal of …, 2021 - Taylor & Francis
Identification of new DPP-IV inhibitors by integrating validated in silico approach is being
presented herein. Novel hits were identified by combining pharmacophore and structure …
presented herein. Novel hits were identified by combining pharmacophore and structure …
[HTML][HTML] 癫痫的治疗和药物发现现状
刘颖， 于海波， 孔庆飞 - 药学学报, 2021 - html.rhhz.net
癫痫是常见的神经系统疾病之一, 以神经元异常放电导致短暂的脑功能障碍为特征,
主要以药物治疗为主. 尽管近年来抗癫痫药物开发有卓越的进展, 但是对于难治性癫痫患者仍 …
主要以药物治疗为主. 尽管近年来抗癫痫药物开发有卓越的进展, 但是对于难治性癫痫患者仍 …