Vitamin E for Alzheimer's dementia and mild cognitive impairment

N Farina, D Llewellyn, MGEKN Isaac… - Cochrane database of …, 2017 - cochranelibrary.com
Background Vitamin E occurs naturally in the diet. It has several biological activities,
including functioning as an antioxidant to scavenge toxic free radicals. Evidence that free …

Preventing dementia? Interventional approaches in mild cognitive impairment

V Lissek, B Suchan - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Mild cognitive impairment (MCI) is defined as an intermediate state between normal
cognitive aging and dementia. It describes a status of the subjective impression of cognitive …

Key questions for the evaluation of anti-amyloid immunotherapies for Alzheimer's disease

KY Liu, N Villain, S Ayton, SF Ackley… - Brain …, 2023 - academic.oup.com
The clinical benefit associated with anti-amyloid immunotherapies, a new class of drugs for
the treatment of Alzheimer's disease, is predicated on their ability to modify disease course …

Venglustat combined with imiglucerase for neurological disease in adults with Gaucher disease type 3: the LEAP trial

R Schiffmann, TM Cox, JF Dedieu, SJM Gaemers… - Brain, 2023 - academic.oup.com
Gaucher disease type 3 is a chronic neuronopathic disorder with wide-ranging effects,
including hepatosplenomegaly, anaemia, thrombocytopenia, skeletal disease and diverse …

Challenges and opportunities of diagnostic markers of Alzheimer's disease based on structural magnetic resonance imaging

X Hu, M Meier, J Pruessner - Brain and Behavior, 2023 - Wiley Online Library
Objectives This article aimed to carry out a narrative literature review of early diagnostic
markers of Alzheimer's disease (AD) based on both micro and macro levels of pathology …

Contribution of neuroimaging to the diagnosis of Alzheimer's disease and vascular dementia

G Román, B Pascual - Archives of medical research, 2012 - Elsevier
The aim of this study was to review, summarize and analyze recent findings relevant to the
contribution of neuroimaging to the diagnosis of Alzheimer's disease (AD) and vascular …

Linear vs volume measures of ventricle size: relation to present and future gait and cognition

JE Crook, JL Gunter, CT Ball, DT Jones… - Neurology, 2020 - AAN Enterprises
Objective To compare the clinical utility of volume-based ratios with the standard linear ratio
of Evans index (EI) by examining their associations with gait, cognition, and other patient …

Cognitive correlates of hippocampal atrophy and ventricular enlargement in adults with or without mild cognitive impairment

N Goukasian, S Porat, A Blanken, D Avila… - Dementia and geriatric …, 2019 - karger.com
We analyzed structural magnetic resonance imaging data from 58 cognitively normal and
101 mild cognitive impairment subjects. We used a general linear regression model to study …

Magnetic resonance imaging relaxation time in Alzheimer's disease

X Tang, F Cai, DX Ding, LL Zhang, XY Cai, Q Fang - Brain research bulletin, 2018 - Elsevier
The magnetic resonance imaging (MRI) relaxation time constants, T1 and T2, are sensitive
to changes in brain tissue microstructure integrity. Quantitative T1 and T2 relaxation times …

High risk of dementia in ventricular enlargement with normal pressure hydrocephalus related symptoms

AM Koivisto, MI Kurki, I Alafuzoff… - Journal of …, 2016 - content.iospress.com
Background: Differential diagnosis of ventricular enlargement with normal pressure
hydrocephalus (NPH) related symptoms is challenging. Patients with enlarged ventricles …