The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription …

Neutrophils are the most abundant myeloid cells in human blood and are emerging as
important regulators of cancer. However, their functional importance has often been …

Neutrophils are cells at the frontline of innate immunity that can quickly activate effector
functions to eliminate pathogens upon stimulation. However, little is known about the …

The overlapping metabolic reprogramming of cancer and immune cells is a putative
determinant of the antitumor immune response in cancer. Increased evidence suggests that …

Background Effective removal of pathogenic bacteria is key to improving the prognosis of
sepsis. Polymorphonuclear neutrophils (PMNs) are the most important components of innate …

Dysregulated neutrophil activation contributes to the pathogenesis of autoimmune diseases
including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Neutrophil …

Rheumatoid arthritis (RA) is a chronic inflammatory disorder affecting synovial joints.
Neutrophils are believed to play an important role in both the initiation and progression of …

Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

Abnormal intracellular metabolism not only provides nutrition for tumor occurrence and
development, but also sensitizes the function of various immune cells in the immune …

Neutrophils are the most abundant circulating leukocytes in humans and the first immune
cells recruited at the site of inflammation. Classically perceived as short-lived effector cells …