Emulsion electrospinning is a novel approach to fabricate core–shell nanofibers, and it is
associated with several advantages such as the alleviation of initial burst release of drugs …

Gating the release of chemical payloads in response to transient signals is an important
feature of 'smart'delivery systems. Herein, we report a triazole-based self-immolative linker …

The aim of this study was to develop clickable prodrugs bearing a tunable pH responsive
linker designed for acidic pH-mediated release of histone deacetylase inhibitors. HDACi are …

Self‐immolative linkers offer efficient mechanisms for deprotecting 'caged'functional groups
in response to specific stimuli. Herein we describe a convenient 'click'chemistry method for …

A range of carbamate functionalized 1, 4-disubstituted triazoles featuring a base sensitive
trigger residue, plus a model aromatic amine reporter group, were prepared via copper (I) …

(−)-Kainic acid potently increases stretch-induced afferent firing in muscle spindles, probably
acting through a hitherto uncloned phospholipase D (PLD)-coupled mGlu receptor …

Two strategies were considered for the synthesis of 2, 3-unsaturated O-glucosyl-1, 2, 3-
triazoles. The first, involving reaction between tri-O-acetyl-d-glucal and triazole alcohols …

ABSTRACT A convenient, efficient and fast acetylation combining clays and ultrasound
irradiation is described. Some molecules from nature or synthetic source, ie, D-glucose …

Triazolyl derivatives of anilines were prepared and evaluated as releasing systems at mildly
acidic pH values. Two triazolyl derivatives showed convenient pH sensitivity, being stable at …

Recent achievements in the nanoparticles-based, especially polymer-based nanoparticles
targeted therapies, are due to the exploitation of particular biological processes found in …