Food allergens are closely related to their gastrointestinal digestion fate, but the changes in
food allergens during digestion and related mechanisms are quite complicated. This review …

Tremendous progress in the last few years has been made to explain how seemingly
harmless environmental proteins from different origins can induce potent Th2‐biased …

Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

Plant non-specific lipid transfer proteins (nsLTPs) are usually defined as small, basic
proteins, with a wide distribution in all orders of higher plants. Structurally, nsLTPs contain a …

Inflammation, which is induced by the immune response, is recognized as the driving factor
in many diseases, including infections and inflammatory diseases, metabolic disorders and …

Many allergens feature hydrophobic cavities that allow the binding of primarily hydrophobic
small‐molecule ligands. Ligand‐binding specificities can be strict or promiscuous. Serum …

Pulmonary respiration inevitably exposes the mucosal surface of the lung to potentially
noxious stimuli, including pathogens, allergens, and particulates, each of which can trigger …

Whereas house dust mite (HDM) allergy results from a dysregulated Th2-biased adaptive
immune response, activation of innate immune signaling pathways is a critical prerequisite …

Aeroallergens or inhalant allergens, are proteins dispersed through the air and have the
potential to induce allergic conditions such as rhinitis, conjunctivitis, and asthma. Outdoor …

Mutated and unmutated IgE and IgG play different and partly opposing roles in allergy
development, but the mechanisms controlling their relative production are incompletely …