A cell cycle centric view of tumour dormancy

WA Weston, AR Barr - British Journal of Cancer, 2023 - nature.com
Tumour dormancy and recurrent metastatic cancer remain the greatest clinical challenge for
cancer patients. Dormant tumour cells can evade treatment and detection, while retaining …

Parameter estimation in the Montijano-Bergues-Bory-Gompertz stochastic model for unperturbed tumor growth

B Bonilla-Capilla, LEB Cabrales - bioRxiv, 2024 - biorxiv.org
Different sources of noises endogenous and exogenous to the cancer are involved in its
stochastic growth. The aim of this study is to propose the stochastic version of Montijano …

Genetic and epigenetic driven variation in regulatory regions activity contribute to adaptation and evolution under endocrine treatment

N Slaven, R Lopes, E Canale, D Ivanoiu, C Pacini… - bioRxiv, 2022 - biorxiv.org
Comprehensive profiling of hormone-dependent breast cancer (HDBC) has identified
hundreds of protein-coding alterations contributing to cancer initiation,, but only a handful …

Deciphering Mutational Signature Dynamics in Hormone-Sensitive Breast Cancer During Treatment Adaptation.

L Magnani, D Ivanoiu, D Rosano, E Sofyali, C James… - 2023 - researchsquare.com
The DNA accumulates somatic changes before and after tumor initiation. These changes
have been classified into mutational signatures (1) but only recently have studies begun to …

[PDF][PDF] Genetic and epigenetic driven variation in regulatory regions activity contribute to adaptation and evolution under endocrine treatment

L Magnani - 2022 - scholar.archive.org
Comprehensive pro ling of hormone-dependent breast cancer (HDBC) has identi ed
hundreds of proteincoding alterations contributing to cancer initiation1, 2, but only a handful …