Lactose is the most commonly used excipient in carrier-based dry powder inhalation (DPI)
formulations. Numerous inhalation therapies have been developed using lactose as a …

Introduction: The effectiveness of drug delivery to the lungs is inextricably linked to the
fundamental interactions that occur between particles and flow in the extrathoracic airway …

The use of computational techniques in the design of dry powder inhalers (DPI), as well as
in unravelling the complex mechanisms of drug aerosolization, has increased significantly in …

Inhalation drug delivery has seen a swift rise in the use of dry powder inhalers (DPIs) to treat
chronic respiratory conditions. However, universal adoption of DPIs has been restrained due …

Fine particle lift and aerodispersion are utilized as specialized technology in pharmaceutical
devices such as dry powder inhalers (DPIs), where the active pharmaceutical ingredient …

The breath-actuated mechanism (BAM) is a mechanical unit included in NEXThaler® with
the role of delaying the emission of the drug until the inhalation flow rate of the patient is …

ABSTRACT Introduction Dry Powder Inhalers (DPIs) continue to be developed to deliver an
expanding range of drugs to treat an ever-increasing range of medical conditions; with each …

The in-vitro aerosol performance of two combination dry powder inhaler (DPI) products,
Foster® NEXThaler® and Seretide® Diskus® were investigated with single particle aerosol …

Powder flowability plays an important role in die filling during tablet manufacturing. The
present study introduces a novel small-scale measuring technique for powder flow. Based …

Powder deaggregation in Dry Powder Inhalers (DPI) with carrier-based formulations is a key
process for the effectiveness of drug administration. Carrier-wall collisions are one of the …