[HTML][HTML] Clinical correlation among male infertility and overall male health: a systematic review of the literature

F Del Giudice, AM Kasman, M Ferro… - … and Clinical Urology, 2020 - ncbi.nlm.nih.gov
Purpose Ongoing evidence has suggested the role of male factor infertility as a potential
predictor of mortality and general health status. The aim of the present review is to update …

[HTML][HTML] Male infertility: a biomarker of individual and familial cancer risk

BM Hanson, ML Eisenberg, JM Hotaling - Fertility and sterility, 2018 - Elsevier
Associations between male infertility and cancer are gaining clinical attention. Relationships
between infertility and cancer have traditionally been studied in women, but recent work has …

RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis

A Reynolds, H Qiao, Y Yang, JK Chen, N Jackson… - Nature …, 2013 - nature.com
Crossing-over ensures accurate chromosome segregation during meiosis, and every pair of
chromosomes obtains at least one crossover, even though the majority of recombination …

[HTML][HTML] New insights to guide patient care: the bidirectional relationship between male infertility and male health

AM Kasman, F Del Giudice, ML Eisenberg - Fertility and Sterility, 2020 - Elsevier
Male reproduction is a complex process, and numerous medical conditions have the
potential to alter spermatogenesis. In addition, male factor infertility may be a biomarker for …

Comparative transcriptomic analysis of spermatozoa from high-and low-fertile crossbred bulls: Implications for fertility prediction

MA Prakash, A Kumaresan… - Frontiers in Cell and …, 2021 - frontiersin.org
Crossbred bulls produced by crossing Bos taurus and Bos indicus suffer with high incidence
of infertility/subfertility problems; however, the etiology remains poorly understood. The …

Epigenetic disruption of the PIWI pathway in human spermatogenic disorders

H Heyn, HJ Ferreira, L Bassas, S Bonache, S Sayols… - PloS one, 2012 - journals.plos.org
Epigenetic changes are involved in a wide range of common human diseases. Although
DNA methylation defects are known to be associated with male infertility in mice, their impact …

Altered miRNA signature of developing germ-cells in infertile patients relates to the severity of spermatogenic failure and persists in spermatozoa

X Muñoz, A Mata, L Bassas, S Larriba - Scientific reports, 2015 - nature.com
The aim of this study was to assess the cellular miRNA expression behaviour in testes with
spermatogenic failure (SpF). We performed a high-throughput screen of 623 mature miRNAs …

[HTML][HTML] Association between male infertility and male-specific malignancies: systematic review and meta-analysis of population-based retrospective cohort studies

F Del Giudice, AM Kasman, E De Berardinis… - Fertility and …, 2020 - Elsevier
Objective To investigate the current evidence that correlates impaired male fertility with the
risk of developing male-related malignancies. Design Systematic review and meta-analysis …

[HTML][HTML] Male fertility as a proxy for health

CC Zhao, M Scott, ML Eisenberg - Journal of Clinical Medicine, 2024 - mdpi.com
Male fertility is affected by a wide range of medical conditions that directly and indirectly
affect spermatogenesis. As such, it can be useful as both an indicator of current health and a …

Male fertility as a marker for health

T Chen, F Belladelli, F Del Giudice… - Reproductive Biomedicine …, 2022 - Elsevier
Male reproduction is a complex biological process, and male factor infertility is increasingly
recognized as a biomarker for overall male health. Emerging data suggest associations …