Personalized medicine has been identified as a powerful tool for addressing the myriad of
health issues facing different health systems globally. Although recent studies have …

Population history-focused DNA and ancient DNA (aDNA) research in Africa has
dramatically increased in the past decade, enabling increasingly fine-scale investigations …

Ancient DNA provides a powerful window into the biology of extant and extinct species,
including humans' closest relatives: Denisovans and Neanderthals. Here, we review what is …

Inborn errors of immunity (IEI) are genetic disorders with extensive clinical presentations.
They can range from increased susceptibility to infections to significant immune …

As a scientific community we assumed that exome sequencing will elucidate the basis of
most heritable diseases. However, it turned out it was not the case; therefore, attention has …

Human genomic diversity has been shaped by both ancient and ongoing challenges from
viruses. The current coronavirus disease 2019 (COVID-19) pandemic caused by severe …

Background Gastric cancer is the sixth most frequently diagnosed cancer and third in
causing cancer-related death globally. The most frequently mutated gene in human cancers …

Increasing diversity in genomic studies is essential to advance precision medicine and
health equity in rheumatic diseases. Addressing structural and logistical barriers to include …

Introduction Africa, a continent considered to be the cradle of human beings has the largest
genetic diversity among its population than other continents. This review discusses the …

Background Intervertebral disc (IVD) degenerative disease is a multifactorial disease for
which genetics plays an integral role. Several genes, and their variants, associated with the …