Plant synthetic biology is an emerging field that combines engineering principles with plant
biology toward the design and production of new devices. This emerging field should play …

Design automation refers to a category of software tools for designing systems that work
together in a workflow for designing, building, testing, and analyzing systems with a target …

Logic and memory are essential functions of circuits that generate complex, state-dependent
responses. Here we describe a strategy for efficiently assembling synthetic genetic circuits …

We present a methodology for the design, construction and modification of synthetic gene
networks. This method emphasizes post-assembly modification of constructs based on …

Highlights•Synthetic biology aims to apply engineering principles in biology.•Insufficient part
libraries, standards, and software are challenges to the field.•Working on the challenges will …

Abstract Background Biological Computer Aided Design (bioCAD) assists the de novo
design and selection of existing genetic components to achieve a desired biological activity …

Genetic designs can consist of dozens of genes and hundreds of genetic parts. After
evaluating a design, it is desirable to implement changes without the cost and burden of …

To perform well in biotechnology applications, synthetic genetic oscillators must be
engineered to allow independent modulation of amplitude and period. This need is currently …

Bio-design automation (BDA) is an emerging field focused on computer-aided design,
engineering principles, and automated manufacturing of biological systems. Here we …

Labor-intensive multistep biological tasks, such as the construction and cloning of DNA
molecules, are prime candidates for laboratory automation. Flexible and biology-friendly …