Abnormalities of insulin metabolism include hyperinsulinaemia and insulin resistance, and
these problems are collectively referred to as insulin dysregulation in this review. Insulin …

Laminitis is one of the most common and frustrating clinical presentations in equine practice.
While the principles of treatment for laminitis have not changed for several decades, there …

Equine metabolic syndrome (EMS) is a widely recognized collection of risk factors for
endocrinopathic laminitis. The most important of these risk factors is insulin dysregulation …

Breed-related differences may occur in the innate insulin sensitivity (SI) of horses and
ponies, an important factor believed to be associated with the risk of laminitis. The aim of this …

Insulin dysregulation is the hallmark of equine metabolic syndrome and has received
attention because of its direct association with laminitis. In the absence of an adequate …

Background The importance of including exercise with dietary modification for the
management of obese equids is not clearly understood. Objectives To evaluate the effect of …

Background Increased blood insulin levels are associated with an increased risk of pasture‐
associated laminitis in equids. Objective To determine the relationship between plasma …

Obesity, lipodystrophy, diabetes, and hypertension collectively constitute the main features
of Metabolic Syndrome (MetS), together with insulin resistance (IR), which is considered as …

Reasons for performing study Treatment of equine metabolic syndrome (EMS) is essential to
improve insulin sensitivity and reduce the risk of laminitis. Calorie restriction and increased …

Metformin may be an effective therapeutic option for insulin-resistant (IR) horses/ponies
because, in humans, it reportedly enhances insulin sensitivity (SI) of peripheral tissues …