Solid-state nanopore sensors

L Xue, H Yamazaki, R Ren, M Wanunu… - Nature Reviews …, 2020 - nature.com
Nanopore-based sensors have established themselves as a prominent tool for solution-
based, single-molecule analysis of the key building blocks of life, including nucleic acids …

In situ solid-state nanopore fabrication

JP Fried, JL Swett, BP Nadappuram, JA Mol… - Chemical Society …, 2021 - pubs.rsc.org
Nanopores in solid-state membranes are promising for a wide range of applications
including DNA sequencing, ultra-dilute analyte detection, protein analysis, and polymer data …

Digital immunoassay for biomarker concentration quantification using solid-state nanopores

L He, DR Tessier, K Briggs, M Tsangaris… - Nature …, 2021 - nature.com
Single-molecule counting is the most accurate and precise method for determining the
concentration of a biomarker in solution and is leading to the emergence of digital diagnostic …

An introduction to nanopore sequencing: past, present, and future considerations

M MacKenzie, C Argyropoulos - Micromachines, 2023 - mdpi.com
There has been significant progress made in the field of nanopore biosensor development
and sequencing applications, which address previous limitations that restricted widespread …

A guide to signal processing algorithms for nanopore sensors

C Wen, D Dematties, SL Zhang - ACS sensors, 2021 - ACS Publications
Nanopore technology holds great promise for a wide range of applications such as
biomedical sensing, chemical detection, desalination, and energy conversion. For sensing …

Label-free optical analysis of biomolecules in solid-state nanopores: toward single-molecule protein sequencing

Y Zhao, M Iarossi, AF De Fazio, JA Huang… - ACS …, 2022 - ACS Publications
Sequence identification of peptides and proteins is central to proteomics. Protein
sequencing is mainly conducted by insensitive mass spectroscopy because proteins cannot …

Solid-State Nanopore Distinguishes Ferritin and Apo-Ferritin with Identical Exteriors through Amplified Flexibility at Single-Molecule Level

YD Yin, FF Chen, J Hu, L Yang, XT Song… - Analytical …, 2023 - ACS Publications
Protein identification and discrimination at the single-molecule level are big challenges.
Solid-state nanopores as a sensitive biosensor have been used for protein analysis …

Electroosmosis in nanopores: computational methods and technological applications

A Gubbiotti, M Baldelli, G Di Muccio… - … in Physics: X, 2022 - Taylor & Francis
Electroosmosis is a fascinating effect where liquid motion is induced by an applied electric
field. Counter ions accumulate in the vicinity of charged surfaces, triggering a coupling …

Solid‐State Quad‐Nanopore Array for High‐Resolution Single‐Molecule Analysis and Discrimination

R Hu, R Zhu, G Wei, Z Wang, ZY Gu… - Advanced …, 2023 - Wiley Online Library
The ability to detect and distinguish biomolecules at the single‐molecule level is at the
forefront of today's biomedicine and analytical chemistry research. Increasing the dwell time …

Solid-state and polymer nanopores for protein sensing: A review

N Meyer, I Abrao-Nemeir, JM Janot, J Torrent… - Advances in colloid and …, 2021 - Elsevier
In two decades, the solid state and polymer nanopores became attractive method for the
protein sensing with high specificity and sensitivity. They also allow the characterization of …