An overview of structurally diversified anticonvulsant agents

F Al-Otaibi - Acta Pharmaceutica, 2019 - hrcak.srce.hr
Sažetak There are several limited approaches to treat epilepsy in hospitals, for example,
using medicines, surgery, electrical stimulation and dietary interventions. Despite the …

Chemical Composition and Antioxidant and Antibacterial Activities of an Essential Oil Extracted from an Edible Seaweed, Laminaria japonica L.

JK Patra, G Das, KH Baek - Molecules, 2015 - mdpi.com
Laminaria japonica L. is among the most commonly consumed seaweeds in northeast Asia.
In the present study, L. japonica essential oil (LJEO) was extracted by microwave …

Synthesis, molecular modeling studies and anticonvulsant activity of certain (1-(benzyl (aryl) amino) cyclohexyl) methyl esters

WH Abd-Allah, ME Aboutabl, MN Aboul-Enein… - Bioorganic …, 2017 - Elsevier
Abstract A series of (1-(benzyl (aryl) amino) cyclohexyl) methyl esters 7a-n were prepared
and screened for their anticonvulsant profile. Screening of these esters 7a-n and their …

Synthesis and Characterization of Novel Schiff Bases Derived from 2-Butyl-4-chloro Imidazole for the Enhanced Antimicrobial Property

S Pandiarajan, N Hajarabeevi, RR Shaikh… - Applied Biochemistry …, 2023 - Springer
In this study, a novel Schiff base was synthesized which comprises a core moiety of 2-butyl-4-
chloro imidazole. The ligand was synthesized by the reaction between the carbonyl …

Experimental and Theoretical Studies of the Vibrational and Electronic Properties of (2E)-2-[3-(1H-imidazol-1-yl)-1-phenyl-propylidene]-N …

M Govindarajan, AS Abdelhameed, AA Al-Saadi… - Applied Sciences, 2015 - mdpi.com
In the current investigation, the molecular structure of the anticonvulsant agent (2 E)-2-[3-(1
H-imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide ((2 E)-HIPC) was …

Pseudo‐MS3 Approach Using Electrospray Mass Spectrometry (ESI‐MS/MS) to Characterize Certain (2E)‐2‐[3‐(1H‐Imidazol‐1‐yl)‐1‐phenylpropylidene] …

AS Abdelhameed, AA Kadi, MI Attia… - Journal of …, 2014 - Wiley Online Library
An approach for the use of in‐source fragmentation with electrospray ionization followed by
product ion scan in a triple quadrupole mass spectrometer system is described. This …

Spectroscopic Investigations, DFT Calculations, and Molecular Docking Studies of the Anticonvulsant (2E)‐2‐[3‐(1H‐Imidazol‐1‐yl)‐1‐phenylpropylidene]‐N‐(4 …

RI Al-Wabli, D Manimaran, L John, IH Joe… - Journal of …, 2016 - Wiley Online Library
Drug discovery for the management of neurological disorders is a challenging arena in
medicinal chemistry. Vibrational spectral studies of (2E)‐2‐[3‐(1H‐imidazol‐1‐yl)‐1 …

Spectroscopic (FT-IR, FT-Raman, UV, 1H and 13C NMR) profiling and theoretical calculations of (2E)-2-[3-(1H-imidazol-1-yl)-1-phenylpropylidene] …

NG Haress, M Govindarajan, RI Al-Wabli… - Journal of Molecular …, 2016 - Elsevier
Vibrational characteristics of the anticonvulsant agent,(2 E)-2-[3-(1H-imidazol-1-yl)-1-
phenylpropylidene] hydrazinecarboxamide ((2E)-IPHC) have been investigated. The …

[PDF][PDF] ПОТЕНЦИАЛ ПРАКТИЧЕСКОЙ ПРИМЕНИМОСТИ ИМИДАЗОЛСОДЕРЖАЩИХ ПРОИЗВОДНЫХ (Oбзор)

АB Kaldybayeva, VKY Yu, АЕ Malmakova… - Chemical Journal of …, 2023 - chemjournal.kz
Introduction. The imidazole ring is becoming a popular structural fragment in synthetic
pharmaceuticals, being an ionizing and aromatic component, which activates …

[PDF][PDF] Research Article Pseudo-MS

AS Abdelhameed, AA Kadi, MI Attia, RF Angawi… - academia.edu
It has always been known that the use of a triple quadrupole mass spectrometer system
(QqQ) for quantitative analysis is superior to that of any ion trap mass spectrometry systems …