Nuclear receptors are intracellular proteins that act as transcription factors. Proteins with
classic nuclear receptor domain structure lacking identified signaling ligands are designated …

Contents Ovulation rate and litter size are important reproduction traits in sheep and are of
high economic value. Reproduction traits typically have low to medium heritabilities and do …

Female fertility requires normal ovarian follicular growth and ovulation. The nuclear receptor
liver receptor homolog 1 has been implicated in processes as diverse as bile acid …

This review focuses on the expression and regulation of 3β-hydroxysteroid
dehydrogenase/Δ5-Δ4 isomerase (3β-HSD), with emphasis on the porcine version. 3β-HSD …

The development of the ovarian follicle to its culmination by ovulation is an essential
element of fertility. The final stages of ovarian follicular growth are characterized by …

Steroidogenic factor-1 (SF-1, also known as Ad4BP) has been demonstrated to be a primary
transcriptional regulator of steroidogenic-related genes. However, mRNA for liver receptor …

Ovaries represent one of the primary steroidogenic organs, producing estrogen and
progesterone under the regulation of gonadotropins during the estrous cycle. Gonadotropins …

Introduction 2.1. Steroidogenesis in the growing follicle 2.2. Steroidogenesis in the corpus
luteum 2.3. WNT/CTNNB1 signaling 3. WNT signaling in the ovary 3.1. Ovarian WNT signals …

The normal menstrual cycle requires a delicate interplay between the hypothalamus,
pituitary and ovary. Therefore, its length is an important indicator of female reproductive …

Steroidogenic factor-1 (SF-1) and liver receptor homolog-1 (LRH-1) belong to the nuclear
receptor superfamily and are categorized as orphan receptors. In addition to other nuclear …