Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update

JM Kyriakis, J Avruch - Physiological reviews, 2012 - journals.physiology.org
The mammalian stress-activated families of mitogen-activated protein kinases (MAPKs)
were first elucidated in 1994, and by 2001, substantial progress had been made in …

Role of p38 MAP kinase signal transduction in solid tumors

HK Koul, M Pal, S Koul - Genes & cancer, 2013 - journals.sagepub.com
Mitogen-activated protein kinases (MAPKs) mediate a wide variety of cellular behaviors in
response to extracellular stimuli. One of the main subgroups, the p38 MAP kinases, has …

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

G Pearson, F Robinson, T Beers Gibson, B Xu… - Endocrine …, 2001 - academic.oup.com
Mitogen-activated protein (MAP) kinases comprise a family of ubiquitous proline-directed,
protein-serine/threonine kinases, which participate in signal transduction pathways that …

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

JM Kyriakis, J Avruch - Physiological reviews, 2001 - journals.physiology.org
The molecular details of mammalian stress-activated signal transduction pathways have
only begun to be dissected. This, despite the fact that the impact of these pathways on the …

Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

C Widmann, S Gibson, MB Jarpe… - Physiological …, 1999 - journals.physiology.org
Widmann, Christian, Spencer Gibson, Matthew B. Jarpe, and Gary L. Johnson. Mitogen-
Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human …

Oxidative stress and gene regulation

RG Allen, M Tresini - Free Radical Biology and Medicine, 2000 - Elsevier
Reactive oxygen species are produced by all aerobic cells and are widely believed to play a
pivotal role in aging as well as a number of degenerative diseases. The consequences of …

MAP kinases

Z Chen, TB Gibson, F Robinson, L Silvestro… - Chemical …, 2001 - ACS Publications
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Chemical Reviews ACS Publications. Most Trusted. Most Cited. Most Read Quick View Share …

Mitogen-activated protein kinases: new signaling pathways functioning in cellular responses to environmental stress

KJ Cowan, KB Storey - Journal of Experimental Biology, 2003 - journals.biologists.com
The mitogen-activated protein kinase (MAPK) superfamily consists of three main protein
kinase families: the extracellular signal-regulated protein kinases (ERKs), the c-Jun N …

[HTML][HTML] MAP kinase pathways

MH Cobb - Progress in biophysics and molecular biology, 1999 - Elsevier
MAP kinases help to mediate diverse processes ranging from transcription of
protooncogenes to programmed cell death. More than a dozen mammalian MAP kinase …

p38 MAPK signalling cascades in inflammatory disease

E Herlaar, Z Brown - Molecular medicine today, 1999 - cell.com
Inflammatory mediators released during acute and chronic diseases activate multiple
intracellular signalling cascades including the mitogen-activated protein kinase (MAPK) …