Perturbations in gut microbiota composition in psychiatric disorders: a review and meta-analysis

VL Nikolova, MRB Smith, LJ Hall, AJ Cleare… - JAMA …, 2021 - jamanetwork.com
Importance Evidence of gut microbiota perturbations has accumulated for multiple
psychiatric disorders, with microbiota signatures proposed as potential biomarkers …

The gut microbiota in anxiety and depression–a systematic review

CA Simpson, C Diaz-Arteche, D Eliby… - Clinical psychology …, 2021 - Elsevier
Growing evidence indicates the community of microorganisms throughout the
gastrointestinal tract,(ie, gut microbiota), is associated with anxiety and depressive …

[HTML][HTML] The role of the gut microbiota in the development and progression of major depressive and bipolar disorder

T Knuesel, MH Mohajeri - Nutrients, 2021 - mdpi.com
A growing number of studies in rodents indicate a connection between the intestinal
microbiota and the brain, but comprehensive human data is scarce. Here, we systematically …

[HTML][HTML] Mining microbes for mental health: determining the role of microbial metabolic pathways in human brain health and disease

S Spichak, TFS Bastiaanssen, K Berding… - Neuroscience & …, 2021 - Elsevier
There is increasing knowledge regarding the role of the microbiome in modulating brain and
behaviour. Indeed, the actions of microbial metabolites are key for appropriate gut-brain …

Ischemia-selective cardioprotection by malonate for ischemia/reperfusion injury

HA Prag, D Aksentijevic, A Dannhorn, AV Giles… - Circulation …, 2022 - Am Heart Assoc
Background: Inhibiting SDH (succinate dehydrogenase), with the competitive inhibitor
malonate, has shown promise in ameliorating ischemia/reperfusion injury. However, key for …

[HTML][HTML] Faecal microbiota transplantation from patients with depression or healthy individuals into rats modulates mood-related behaviour

JK Knudsen, TY Michaelsen, C Bundgaard-Nielsen… - Scientific reports, 2021 - nature.com
Differences in gut microbiota composition have been observed in patients with major
depressive disorder (MDD) compared to healthy individuals. Here, we investigated if faecal …

Gut microbiota changes in patients with bipolar depression

S Hu, A Li, T Huang, J Lai, J Li, ME Sublette… - Advanced …, 2019 - Wiley Online Library
This study aims to characterize the gut microbiota in depressed patients with bipolar
disorder (BD) compared with healthy controls (HCs), to examine the effects of quetiapine …

Gut microbiota variations in patients diagnosed with major depressive disorder—A systematic review

JK Knudsen, C Bundgaard‐Nielsen… - Brain and …, 2021 - Wiley Online Library
Objective The etiology of major depressive disorder (MDD) is multi‐factorial and has been
associated with a perturbed gut microbiota. Thus, it is therefore of great importance to …

[HTML][HTML] Multi-cohort analysis of depression-associated gut bacteria sheds insight on bacterial biomarkers across populations

S Liang, ZY Sin, J Yu, S Zhao, Z Xi, R Bruzzone… - Cellular and Molecular …, 2023 - Springer
Gut microbes are associated with the development of depression based on extensive
evidence. However, previous studies have led to conflicting reports on this association …

[HTML][HTML] Gut microbiome: A potential indicator for predicting treatment outcomes in major depressive disorder

Z Dong, X Shen, Y Hao, J Li, H Xu, L Yin… - Frontiers in …, 2022 - frontiersin.org
The therapeutic outcomes in major depressive disorder (MDD), one of the most common
and heterogeneous mental illnesses, are affected by factors that remain unclear and often …