Pediatric-inspired treatment regimens for adolescents and young adults with Philadelphia chromosome–negative acute lymphoblastic leukemia: a review

SE Siegel, W Stock, RH Johnson, A Advani… - JAMA …, 2018 - jamanetwork.com
Importance The incidence of acute lymphoblastic leukemia (ALL) and lymphoblastic
lymphoma (LBL) in adolescent and young adult (AYA) patients (age range, 15-39 years) in …

[HTML][HTML] Optimizing use of L-asparaginase–based treatment of adults with acute lymphoblastic leukemia

D Douer, N Gökbuget, W Stock, N Boissel - Blood reviews, 2022 - Elsevier
Acute lymphoblastic leukemia (ALL) is a malignancy of lymphoid progenitor cells occurring
at an annual incidence rate of approximately 1.1–2.1 per 100,000 person-years globally …

Acute lymphoblastic leukemia and lymphoblastic lymphoma in adolescents and young adults

JL McNeer, A Bleyer - Pediatric blood & cancer, 2018 - Wiley Online Library
Compared to younger and older age groups, the incidence of acute lymphoblastic leukemia
(ALL) and lymphoblastic lymphoma (LBL) has increased more in the adolescent and young …

Treatment of young adults with Philadelphia‐negative acute lymphoblastic leukemia and lymphoblastic lymphoma: hyper‐CVAD vs. pediatric‐inspired regimens

SE Siegel, A Advani, N Seibel, L Muffly… - American journal of …, 2018 - Wiley Online Library
For young adults with acute lymphoblastic leukemia, pediatric‐based regimens are likely to
provide the following when compared to hyper‐CVAD regimens: better disease control, less …

Philadelphia-like acute lymphoblastic leukemia: the journey from molecular background to the role of bone marrow transplant

R Alghandour, DH Sakr, Y Shaaban - Annals of Hematology, 2023 - Springer
Philadelphia chromosome-like (Ph-like) ALL is a recent subtype of acute lymphoblastic
leukemia. Although it does not express the BCR-ABL fusion gene, it has a behavior like true …

[HTML][HTML] How I diagnose and manage Philadelphia chromosome-like acute lymphoblastic leukemia

A Frisch, Y Ofran - Haematologica, 2019 - ncbi.nlm.nih.gov
Advances in our understanding of mechanisms of leukemogenesis and driver mutations in
acute lymphoblastic leukemia (ALL) lead to a more precise and informative sub …

Important factors improving outcome of young adults with acute lymphoblastic leukemia (ALL)

A Bleyer - Best Practice & Research Clinical Haematology, 2021 - Elsevier
Four categories of important factors improving outcome of young adults and older
adolescents with acute lymphoblastic leukemia (ALL) are biologic type, clinical trials …

Comparison of a modified pediatric protocol versus a hyper-CVAD protocol in adolescents and young adults with Philadelphia-negative acute lymphoblastic leukemia …

H Salama, S Eldadah, MH Omer, A Alhejazi, LB Dayil… - Leukemia Research, 2023 - Elsevier
Abstract Background The outcomes of Pediatric acute lymphoblastic leukemia (ALL) have
improved dramatically whereas outcomes for ALL amongst adolescents and young adults …

Survival analysis of adult patients with ALL in Mexico City: first report from the Acute Leukemia Workgroup (ALWG)(GTLA)

E Crespo‐Solis, K Espinosa‐Bautista… - Cancer …, 2018 - Wiley Online Library
Acute lymphoblastic leukemia (ALL) is a hematologic malignancy characterized by the
clonal expansion of hematopoietic lymphoid progenitors. With new target therapies, the …

Clinical experience with frontline Hyper-CVAD-based regimens, including Hyper-CVAD plus ponatinib, in patients with acute lymphoblastic leukemia treated at a …

T Othman, BN Moskoff, G Ho, ME Tenold, T Azenkot… - Leukemia Research, 2022 - Elsevier
Background Hyper-CVAD is an established regimen for adult ALL that was developed at the
MD Anderson Cancer Center (MDACC). However, results can vary across different …