High fat diet-triggered non-alcoholic fatty liver disease: A review of proposed mechanisms

CY Lian, ZZ Zhai, ZF Li, L Wang - Chemico-biological interactions, 2020 - Elsevier
Obesity is characterized by the deposition of excessive body fat, and is caused by energy
imbalance, especially when consuming fat-rich diets. High fat diet (HFD)-associated obesity …

Diet and male fertility: the impact of nutrients and antioxidants on sperm energetic metabolism

A Ferramosca, V Zara - International journal of molecular sciences, 2022 - mdpi.com
Diet might affect male reproductive potential, but the biochemical mechanisms involved in
the modulation of sperm quality remain poorly understood. While a Western diet is …

Targeting mitochondrial ROS-mediated ferroptosis by quercetin alleviates high-fat diet-induced hepatic lipotoxicity

JJ Jiang, GF Zhang, JY Zheng, JH Sun… - Frontiers in …, 2022 - frontiersin.org
Background: The protective effect of quercetin on nonalcoholic fatty liver disease (NAFLD)
has been reported, but its mechanism remains poorly understood. Recently, quercetin was …

Inhibitory effect of astaxanthin on oxidative stress-induced mitochondrial dysfunction-a mini-review

SH Kim, H Kim - Nutrients, 2018 - mdpi.com
Oxidative stress is a major contributor to the pathogenesis of various human diseases as
well as to the aging process. Mitochondria, as the center of cellular metabolism and major …

Nutritional importance of carotenoids and their effect on liver health: A review

LI Elvira-Torales, J García-Alonso, MJ Periago-Castón - Antioxidants, 2019 - mdpi.com
The consumption of carotenoids has beneficial effects on health, reducing the risk of certain
forms of cancer, cardiovascular diseases, and macular degeneration, among others. The …

Nonalcoholic fatty liver disease (NAFLD). Mitochondria as players and targets of therapies?

A Di Ciaula, S Passarella, H Shanmugam… - International Journal of …, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and
represents the hepatic expression of several metabolic abnormalities of high epidemiologic …

[HTML][HTML] Silica nanoparticles aggravated the metabolic associated fatty liver disease through disturbed amino acid and lipid metabolisms-mediated oxidative stress

A Abulikemu, X Zhao, H Xu, Y Li, R Ma, Q Yao, J Wang… - Redox Biology, 2023 - Elsevier
The metabolic associated fatty liver disease (MAFLD) is a public health challenge, leading to
a global increase in chronic liver disease. The respiratory exposure of silica nanoparticles …

Role of mitochondria in liver metabolic health and diseases

B Morio, B Panthu, A Bassot, J Rieusset - Cell Calcium, 2021 - Elsevier
The liver is a major organ that coordinates the metabolic flexibility of the whole body, which
is characterized by the ability to adapt dynamically in response to fluctuations in energy …

The effects of probiotics on small intestinal microbiota composition, inflammatory cytokines and intestinal permeability in patients with non-alcoholic fatty liver disease

N Ayob, KN Muhammad Nawawi, MH Mohamad Nor… - Biomedicines, 2023 - mdpi.com
The prevalence of non-alcoholic fatty liver disease (NAFLD) has soared globally. As our
understanding of the disease grows, the role of the gut-liver axis (GLA) in NAFLD …

The role of resveratrol in liver disease: A comprehensive review from in vitro to clinical trials

C Izzo, M Annunziata, G Melara, R Sciorio, M Dallio… - Nutrients, 2021 - mdpi.com
Many studies have shown that resveratrol has a lot of therapeutic effects on liver disorders.
Its administration can significantly increase the survival rate after liver transplantation …