[HTML][HTML] Imaging as an outcome measure in multiple sclerosis

D Ontaneda, RJ Fox - Neurotherapeutics, 2017 - Elsevier
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system.
Magnetic resonance imaging (MRI) is sensitive to lesion formation both in the brain and …

Deep learning for predicting enhancing lesions in multiple sclerosis from noncontrast MRI

PA Narayana, I Coronado, SJ Sujit, JS Wolinsky… - Radiology, 2020 - pubs.rsna.org
Background Enhancing lesions on MRI scans obtained after contrast material administration
are commonly thought to represent disease activity in multiple sclerosis (MS); it is desirable …

Intra-and interscanner variability of magnetic resonance imaging based volumetry in multiple sclerosis

V Biberacher, P Schmidt, A Keshavan, CC Boucard… - Neuroimage, 2016 - Elsevier
Brain volumetric measurements in multiple sclerosis (MS) reflect not only disease-specific
processes but also other sources of variability. The latter has to be considered especially in …

Feasibility of detecting atrophy relevant for disability and cognition in multiple sclerosis using 3D-FLAIR

S Noteboom, DR van Nederpelt, A Bajrami… - Journal of …, 2023 - Springer
Background and objectives Disability and cognitive impairment are known to be related to
brain atrophy in multiple sclerosis (MS), but 3D-T1 imaging required for brain volumetrics is …

Disease correlates of rim lesions on quantitative susceptibility mapping in multiple sclerosis

M Marcille, S Hurtado Rúa, C Tyshkov, A Jaywant… - Scientific Reports, 2022 - nature.com
Quantitative susceptibility mapping (QSM), an imaging technique sensitive to brain iron, has
been used to detect paramagnetic rims of iron-laden active microglia and macrophages in a …

Detection of grey matter microstructural substrates of neurodegeneration in multiple sclerosis

EA Krijnen, AW Russo, E Salim Karam… - Brain …, 2023 - academic.oup.com
Multiple sclerosis features complex pathological changes in grey matter that begin early and
eventually lead to diffuse atrophy. Novel approaches to image grey-matter microstructural …

Identifying morphological patterns of hippocampal atrophy in patients with mesial temporal lobe epilepsy and Alzheimer disease

Y Duan, Y Lin, D Rosen, J Du, L He, Y Wang - Frontiers in Neurology, 2020 - frontiersin.org
Purpose: Mesial temporal lobe epilepsy (MTLE) and Alzheimer's disease (AD) are two
distinct neurological disorders associated with hippocampal atrophy. Our goal is to analyze …

Classification of radiologically isolated syndrome and clinically isolated syndrome with machine‐learning techniques

V Mato‐Abad, A Labiano‐Fontcuberta… - European journal of …, 2019 - Wiley Online Library
Background and purpose The unanticipated detection by magnetic resonance imaging
(MRI) in the brain of asymptomatic subjects of white matter lesions suggestive of multiple …

Gray matter involvement in radiologically isolated syndrome

A Labiano-Fontcuberta, V Mato-Abad, J Alvarez-Linera… - Medicine, 2016 - journals.lww.com
The unanticipated magnetic resonance imaging (MRI) detection in the brain of asymptomatic
subjects of white matter lesions suggestive of multiple sclerosis has recently been named as …

Critical analysis on the present methods for brain volume measurements in multiple sclerosis

YD Fragoso, PR Willie, MVM Goncalves… - Arquivos de Neuro …, 2017 - SciELO Brasil
Objective The treatment of multiple sclerosis (MS) has quickly evolved from a time when
controlling clinical relapses would suffice, to the present day, when complete disease control …