The pathogenesis of rheumatoid arthritis
S Alivernini, GS Firestein, IB McInnes - Immunity, 2022 - cell.com
Significant recent progress in understanding rheumatoid arthritis (RA) pathogenesis has led
to improved treatment and quality of life. The introduction of targeted-biologic and-synthetic …
to improved treatment and quality of life. The introduction of targeted-biologic and-synthetic …
Synovial tissue macrophages in joint homeostasis, rheumatoid arthritis and disease remission
M Kurowska-Stolarska, S Alivernini - Nature Reviews Rheumatology, 2022 - nature.com
Synovial tissue macrophages (STMs) were principally recognized as having a pro-
inflammatory role in rheumatoid arthritis (RA), serving as the main producers of pathogenic …
inflammatory role in rheumatoid arthritis (RA), serving as the main producers of pathogenic …
[HTML][HTML] Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes
Rheumatoid arthritis is a prototypical autoimmune disease that causes joint inflammation
and destruction. There is currently no cure for rheumatoid arthritis, and the effectiveness of …
and destruction. There is currently no cure for rheumatoid arthritis, and the effectiveness of …
Immune system adaptation during gender-affirming testosterone treatment
Infectious, inflammatory and autoimmune conditions present differently in males and
females. SARS-CoV-2 infection in naive males is associated with increased risk of death …
females. SARS-CoV-2 infection in naive males is associated with increased risk of death …
Immune mechanisms in inflammatory anemia
SP Canny, SL Orozco, NK Thulin… - Annual review of …, 2023 - annualreviews.org
Maintaining the correct number of healthy red blood cells (RBCs) is critical for proper
oxygenation of tissues throughout the body. Therefore, RBC homeostasis is a tightly …
oxygenation of tissues throughout the body. Therefore, RBC homeostasis is a tightly …
Advanced methods and novel biomarkers in autoimmune diseases‑a review of the recent years progress in systemic lupus erythematosus
KA Fenton, HL Pedersen - Frontiers in Medicine, 2023 - frontiersin.org
There are several autoimmune and rheumatic diseases affecting different organs of the
human body. Multiple sclerosis (MS) mainly affects brain, rheumatoid arthritis (RA) mainly …
human body. Multiple sclerosis (MS) mainly affects brain, rheumatoid arthritis (RA) mainly …
SLAMF7 as a promising immunotherapeutic target in multiple myeloma treatments
E Chu, J Wu, SS Kang, Y Kang - Current Oncology, 2023 - mdpi.com
Multiple myeloma (MM) is a common hematological malignancy that has fostered several
new therapeutic approaches to combat newly diagnosed or relapsed MM. While the field …
new therapeutic approaches to combat newly diagnosed or relapsed MM. While the field …
Protective intravenous BCG vaccination induces enhanced immune signaling in the airways
Abstract Intradermal (ID) Bacillus Calmette–Guérin (BCG) is the most widely administered
vaccine in the world. However, ID-BCG fails to achieve the level of protection needed in …
vaccine in the world. However, ID-BCG fails to achieve the level of protection needed in …
Identification and elucidation of cross talk between SLAM Family Member 7 (SLAMF7) and Toll-like receptor (TLR) pathways in monocytes and macrophages
To further elucidate the expression, regulation and function of Signaling Lymphocytic
Activation Molecule Family (SLAMF) protein members in human monocytes and …
Activation Molecule Family (SLAMF) protein members in human monocytes and …
ALKBH5 mediates silica particles-induced pulmonary inflammation through increased m6A modification of Slamf7 and autophagy dysfunction
H Yin, P Gu, Y Xie, X You, Y Zhang, Y Yao… - Journal of Hazardous …, 2024 - Elsevier
Silica particles are commonly encountered in natural and industrial activities. Long-term
environmental exposure to silica can result in silicosis, which is characterized by chronic …
environmental exposure to silica can result in silicosis, which is characterized by chronic …