Release kinetics–concepts and applications

MP Paarakh, PA Jose, CM Setty… - International Journal of …, 2018 - ijprt.org
The release of drug from the formulations plays significant role especially when it comes to
modified release as well as in immediate release dosage forms. Several factors like …

Factors affecting mechanism and kinetics of drug release from matrix-based oral controlled drug delivery systems

MVS Varma, AM Kaushal, A Garg, S Garg - American Journal of drug …, 2004 - Springer
Matrix technologies have often proven popular among the oral controlled drug delivery
technologies because of their simplicity, ease in manufacturing, high level of reproducibility …

Development and evaluation of a multiple-unit oral sustained release dosage form for S (+)-ibuprofen: preparation and release kinetics

PJ Cox, KA Khan, DL Munday… - International journal of …, 1999 - Elsevier
Mini-matrix tablets containing S (+)-ibuprofen have been prepared by the wet granulation
method. The hydrophilic matrix was formed with either xanthan gum, karaya gum or …

Formulation study and drug release mechanism of a new theophylline sustained-release preparation

T Hayashi, H Kanbe, M Okada, M Suzuki… - International journal of …, 2005 - Elsevier
Two matrix theophylline tablets with different release mechanisms were compared. Tablet A
was a swelling/disintegration-type wax matrix made of hydrophobic wax granules, consisting …

Artificial neural networks in the modeling and optimization of aspirin extended release tablets with Eudragit L 100 as matrix substance

S Ibrić, M Jovanović, Z Djurić, J Parojčić, SD Petrović… - Aaps Pharmscitech, 2003 - Springer
The purpose of the present study was to model the effects of the concentration of Eudragit L
100 and compression pressure as the most important process and formulation variables on …

Investigation of Dispersion Kinetics of Particulate Lubricants and their Effect on the Mechanical Strength of MCC Tablets

D Puckhaber, A Kwade, JH Finke - Pharmaceutical Research, 2023 - Springer
Introduction Tablets are commonly produced by internally adding particulate lubricants,
which are known to possibly lower the mechanical strength of tablets. This reduction is …

ANN in pharmaceutical product and process development

MK Das, T Chakraborty - Artificial neural network for drug design, delivery …, 2016 - Elsevier
Artificial neural networks (ANNs) are computer systems developed to mimic the operations
of the human brain by mathematically modeling its neurophysiological structure. Neural …

Polymers used in pharmaceutical industry for oral delivery: insight to synthesis, structure–activity relationship, and recent applications

D Mori, K Dudhat, M Soniwala, R Parmar, D Suthar… - Polymer Bulletin, 2024 - Springer
For a long time, polymers have played a critical role in the pharmaceutical industry for
developing safe, effective, and deliverable dosage forms. Among all the dosage forms oral …

[PDF][PDF] Formulation and in-vitro evaluation of terbutaline sulphate sustained release tablets

R Kola, DN Ramani, PB Kumar - Indian Journal of Research in Pharmacy …, 2013 - ijrpb.com
Sustain release formulation maintain a constant level plasma concentration of drug so that
multiple and night dosing can be avoided. Terbutaline sulphate is a β2 stimulant drug which …

[PDF][PDF] 聚甲丙烯酸铵酯Ⅱ 黏度测定方法

陆明, 王林波, 韩鹏, 陈祝康, 杨美成, 陈桂良 - 医药导报, 2012 - yydbzz.com
摘要目的研究聚甲丙烯酸铵酯Ⅱ 的流体特性并建立其动力黏度测定方法. 方法采用马尔文
Kinexus Ultra 同轴圆筒式流变仪, 温度20℃, 剪切速率10 s-1 条件下测定动力黏度. 结果6 …