Current developments of gene therapy in human diseases

F Liu, R Li, Z Zhu, Y Yang, F Lu - MedComm, 2024 - Wiley Online Library
Gene therapy has witnessed substantial advancements in recent years, becoming a
constructive tactic for treating various human diseases. This review presents a …

[HTML][HTML] DNA polymer conjugates: Revolutionizing neurological disorder treatment through targeted drug delivery

P Panda, SS Kar, R Mohapatra - Next Materials, 2025 - Elsevier
Neurological disorders present a formidable challenge to modern medicine due to their
complex etiology and limited treatment options. Traditional therapeutic approaches often …

Layer-by-layer nanocomposite based on zein and hyaluronic acid for tumor-targeted gene delivery

L Liu, T Wang, Y Sun, G Qi, J Guan, P Lv… - Industrial Crops and …, 2024 - Elsevier
Gene vectors provide a viable approach to ensuring that therapeutic genes reach the target
cells. Polyethyleneimine (PEI), a cationic polymer, was brought into focus on high …

A biocompatible glycogen based nanoparticle coating with lipid bilayer for intracellular delivery of survivin siRNA to HeLa cells

Z Chen, M Su, J Xu, J Li, G Wangcao, L Qiu - Journal of Drug Delivery …, 2024 - Elsevier
In recent years, gene therapy has drawn great attention in the field of cancer treatment for
high efficacy, selectivity, and few adverse effects. Many vectors have been developed for …

[PDF][PDF] Study of amides and polyamides synthesized from biodegradable carboxylic acids

SS Panchal, DV Vasava, R Joshi - RASĀYAN J Chem, 2024 - rasayanjournal.co.in
ABSTRACT A series of seven novel amorphous amides and polyamides were synthesized
from four biodegradable carboxylic acids by direct polycondensation with aliphatic diamines …

Cationic cycloamylose based nucleic acid nanocarriers.

P Prasher, M Sharma, V Agarwal, SK Singh… - Chemico-Biological …, 2024 - Elsevier
Nucleic acid delivery by viral and non-viral methods has been a cornerstone for the
contemporary gene therapy aimed at correcting the defective genes, replacing of the …

Synthesis and study of AB2-type miktoarm star-shaped nanomaterials having glycine as an arm

SS Panchal, DV Vasava - Journal of Polymer Research, 2024 - Springer
Coupling-onto approach was equipped to synthesis seven AB2-type miktoarm stars
nanomaterials using carbodiimide chemistry. Glycine, the simplest amino acid is chosen as …

[PDF][PDF] Biobased Polylactide Nanoparticles as Novel Gene Delivery Nanoplatforms: Can They Be Used for DNA Transport?

FS Fattahi - Nanochemistry Research, 2024 - academia.edu
Gene A gene is the basic physical unit of heredity, a linear sequence of nucleotides along a
segment of DNA that provides the coded instructions for synthesis of RNA; upon translated …