Cypermethrin induces apoptosis, autophagy and inflammation via ERS-ROS-NF-κB axis in hepatocytes of carp (Cyprinus carpio)
D Li, K Zhang, C Xu, Y Jiang, J Shan, Z Zhang… - Pesticide Biochemistry …, 2023 - Elsevier
Abstract Cypermethrin (CYP, IUPAC name:[cyano-(3-phenoxyphenyl) methyl] 3-(2, 2-
dichloroethenyl)-2, 2-dimethylcyclopropane-1-carboxylate) is a pyrethroid insecticide that …
dichloroethenyl)-2, 2-dimethylcyclopropane-1-carboxylate) is a pyrethroid insecticide that …
Hepatoprotective and antioxidant effects of nanopiperine against Cypermethrin via mitigation of oxidative stress, inflammations and gene expression using qRT-PCR
Cypermethrin (Cyp) is a pyrethroid that has been associated with the toxicity of various
organs. The aim of our study was to evaluate the hepatoprotective and antioxidant activities …
organs. The aim of our study was to evaluate the hepatoprotective and antioxidant activities …
Curcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway
D Ding, G Liu, J Yan, Q Zhang, F Meng, L Wang - Plos one, 2024 - journals.plos.org
This study explored the mechanism of curcumin (CUR) suppressing osteoclastogenesis and
evaluated its effects on osteoarthritis (OA) mouse. Bone marrow-derived macrophages were …
evaluated its effects on osteoarthritis (OA) mouse. Bone marrow-derived macrophages were …
Nanocurcumin prevents memory impairment, hippocampal apoptosis, Akt and CaMKII-α signaling disruption in the central STZ model of Alzheimer's disease in rat
The central route of streptozotocin (STZ) administration has been introduced as a rat model
of sporadic Alzheimer's disease (AD). Curcumin was suggested to possess possible …
of sporadic Alzheimer's disease (AD). Curcumin was suggested to possess possible …
Nephrotoxic effect of cypermethrin ameliorated by nanocurcumin through antioxidative mechanism
Cypermethrin is a pyrethroid showing nephrotoxicity by generating ROS-impaired oxidative
stress and changes in inflammatory and apoptotic markers. The harmful consequences are …
stress and changes in inflammatory and apoptotic markers. The harmful consequences are …
Determining the anticancer effect of Gefitinib-loaded NLCs through investigating the inflammatory cytokine (JAK-STAT) pathway
This research aims to investigate the feasibility of using nanostructured lipid carriers (NLC)
loaded with Gefitinib to treat colorectal cancer by focusing on the inflammatory cytokine …
loaded with Gefitinib to treat colorectal cancer by focusing on the inflammatory cytokine …
Sex-Specific Cypermethrin Induced Hippocampal Neurotoxicity Is Via the Modulation of Signaling Molecules for Antioxidant Defense, Membrane Integrity, Apoptosis …
Pesticides, despite their intended use against pests, can have detrimental effects on non-
target organisms, including humans. Its main route of exposure in urban areas is through …
target organisms, including humans. Its main route of exposure in urban areas is through …
Effect of chrysin on oxidative stress, biochemical, and inflammatory alterations in Wistar albino rats exposed to cypermethrin
Cypermethrin is a broad-spectrum pesticide commonly used in agricultural, veterinary and
household applications. Cypermethrin, being a neurotoxic agent and due to its hydrophobic …
household applications. Cypermethrin, being a neurotoxic agent and due to its hydrophobic …