Modification of lipid-based nanoparticles: An efficient delivery system for nucleic acid-based immunotherapy
Lipid-based nanoparticles (LBNPs) are biocompatible and biodegradable vesicles that are
considered to be one of the most efficient drug delivery platforms. Due to the prominent …
considered to be one of the most efficient drug delivery platforms. Due to the prominent …
[HTML][HTML] Delivery of therapeutic oligonucleotides in nanoscale
Therapeutic oligonucleotides (TOs) represent one of the most promising drug candidates in
the targeted cancer treatment due to their high specificity and capability of modulating …
the targeted cancer treatment due to their high specificity and capability of modulating …
Targeted suppression of miRNA-33 using pHLIP improves atherosclerosis regression
X Zhang, N Rotllan, A Canfrán-Duque, J Sun… - Circulation …, 2022 - Am Heart Assoc
Background: miRNA therapeutics have gained attention during the past decade. These
oligonucleotide treatments can modulate the expression of miRNAs in vivo and could be …
oligonucleotide treatments can modulate the expression of miRNAs in vivo and could be …
[HTML][HTML] Protein adsorption determines pulmonary cell uptake of lipid-based nanoparticles
The inhalable administration of lipid nanoparticles is an effective strategy for localised
delivery of therapeutics against various lung diseases. Of this, improved intracellular …
delivery of therapeutics against various lung diseases. Of this, improved intracellular …
RGD peptide‐based target drug delivery of doxorubicin nanomedicine
ABSTRACT Preclinical Research Doxorubicin (DOX) is commonly used for the treatment of
breast cancer and lymphoma. However, its clinical use has been severely limited due to …
breast cancer and lymphoma. However, its clinical use has been severely limited due to …
miRNA delivery by nanosystems: state of the art and perspectives
MicroRNAs (miRNAs) are short (~ 21–23 nucleotides), non-coding endogenous RNA
molecules that modulate gene expression at the post-transcriptional level via the …
molecules that modulate gene expression at the post-transcriptional level via the …
miRacle of microRNA-driven cancer nanotherapeutics
Simple Summary The discovery of microRNAs has revolutionized the world of science and
opened up new opportunities in cancer treatment. miRNA dysregulation plays a crucial role …
opened up new opportunities in cancer treatment. miRNA dysregulation plays a crucial role …
Lipid nanocarriers for microRNA delivery
M Scheideler, I Vidakovic, R Prassl - Chemistry and physics of lipids, 2020 - Elsevier
Non-coding RNAs (ncRNAs) like microRNAs (miRNAs) or small interference RNAs (siRNAs)
with their power to selectively silence any gene of interest enable the targeting of so far …
with their power to selectively silence any gene of interest enable the targeting of so far …
Nanoscale delivery systems for microRNAs in cancer therapy
S Boca, D Gulei, AA Zimta, A Onaciu, L Magdo… - Cellular and Molecular …, 2020 - Springer
Concomitant with advances in research regarding the role of miRNAs in sustaining
carcinogenesis, major concerns about their delivery options for anticancer therapies have …
carcinogenesis, major concerns about their delivery options for anticancer therapies have …
MicroRNAs in non‐small cell lung cancer: Gene regulation, impact on cancer cellular processes, and therapeutic potential
H Petrek, AM Yu - Pharmacology research & perspectives, 2019 - Wiley Online Library
Lung cancer remains the most lethal cancer among men and women in the United States
and worldwide. The majority of lung cancer cases are classified as non‐small cell lung …
and worldwide. The majority of lung cancer cases are classified as non‐small cell lung …