K Ishiwata - Annals of nuclear medicine, 2019 - Springer
10 B-Borono-2-18 F-fluoro-l-phenylalanine (18 F-FBPA) was developed for monitoring the pharmacokinetics of 4-10 B-borono-l-phenylalanine (10 B-BPA) used in boron neutron …
T Nomoto, Y Inoue, Y Yao, M Suzuki, K Kanamori… - Science …, 2020 - science.org
In the current clinical boron neutron capture therapy (BNCT), p-boronophenylalanine (BPA) has been the most powerful drug owing to its ability to accumulate selectively within cancers …
K Mishiro, S Imai, Y Ematsu, K Hirose… - Journal of Medicinal …, 2022 - ACS Publications
A boron neutron capture therapy (BNCT) system, using boron-10-introduced agents coupled with companion diagnostics, is anticipated as a promising cancer theranostic. Thus, this …
R Kawasaki, H Hirano, K Yamana, H Isozaki… - … , Biology and Medicine, 2023 - Elsevier
Boron neutron capture therapy shows is a promising approach to cancer therapy, but the delivery of effective boron agents is challenging. To address the requirements for efficient …
AM Hughes - Expert Reviews in Molecular Medicine, 2022 - cambridge.org
Boron neutron capture therapy (BNCT) is a tumour selective particle radiotherapy, based on the administration of boron carriers incorporated preferentially by tumour cells, followed by …
T Tsurubuchi, M Shirakawa, W Kurosawa, K Matsumoto… - Cells, 2020 - mdpi.com
Boron neutron capture therapy (BNCT) is a unique anticancer technology that has demonstrated its efficacy in numerous phase I/II clinical trials with boronophenylalanine …
E Zavjalov, A Zaboronok, V Kanygin… - … journal of radiation …, 2020 - Taylor & Francis
Purpose: To evaluate the efficacy of boron neutron capture therapy (BNCT) for a heterotopic U87 glioblastoma model in SCID mice using boron phenylalanine (BPA), sodium …
T Watanabe, Y Sanada, Y Hattori… - Journal of Radiation …, 2023 - academic.oup.com
Boron neutron capture therapy (BNCT) is a binary cancer therapy that involves boron administration and neutron irradiation. The nuclear reaction caused by the interaction of …
Boron neutron capture therapy (BNCT) is a highly targeted, selective and effective technique to cure various types of cancers, with less harms to the healthy cells. In principle, BNCT …