Our current food system relies on unsustainable practices, which often fail to provide healthy
diets to a growing population. Therefore, there is an urgent demand for new sustainable …

Abstract Machine learning provides researchers a unique opportunity to make metabolic
engineering more predictable. In this review, we offer an introduction to this discipline in …

The current food production system is negatively impacting planetary and human health. A
transition to a sustainable and fair food system is urgently needed. Microorganisms are likely …

Metabolic engineers endeavor to create a bio-based manufacturing industry using microbes
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …

Terpenoids are the most diverse group of specialized metabolites with numerous
applications. Their biosynthesis is based on the five-carbon isoprene building block and, as …

Microbial fermentations are used for the sustainable production of a range of products. Due
to increasing trends in the food sector toward plant-based foods and meat and dairy product …

Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules
such as renewable biofuels or anticancer drugs. However, traditional synthetic biology …

Aroma compounds provide attractiveness and variety to alcoholic beverages. We discuss
the molecular biology of a major subset of beer aroma volatiles, fruity and floral compounds …

A recent rise in the global brewery sector has increased the demand for high-quality, late
summer hops. The effects of ongoing and predicted climate change on the yield and aroma …

Highlights•Application of machine learning in biotechnology is becoming essential.•Machine
learning is increasingly applied to advance systems metabolic engineering.•Machine …