In this review article we discuss some of the key aspects concerning the development of a
polymer-based nanoparticle formulation for intravenous drug delivery. Since numerous …

The architecture, composition and molecular weight (MW) of polymers and copolymers
made via free radical polymerization are important parameters that affect the end-use of both …

Trabectedin (TRB) and Lurbinectedin (LUR) are alkaloid compounds originally isolated from
Ecteinascidia turbinata with proven antitumoral activity. Both molecules are structural …

Several efforts have been extensively accomplished for the amelioration of the cancer
treatments using different types of new drugs and less invasives therapies in comparison …

Cell-selective drug release in the central nervous system (CNS) holds great promise for the
treatment of many CNS disorders but it is still challenging. We previously demonstrated that …

Tailor-made materials for biomedical applications can be constructed with different building
blocks to confer multiple functions on one platform. Here, we demonstrate the facile …

Trabectedin, a tetrahydroisoquinoline alkaloid, is the first marine antineoplastic agent
approved with special anticancer mechanisms involving DNA binding, DNA repair …

Biodegradable nanoparticles (NPs) have shown great promise as intracellular imaging
probes, nanocarriers and drug delivery vehicles. In this study, we designed and prepared …

Polyester-based nanoparticles (NPs) are among the most adopted drug delivery systems
developed so far. This is mainly due to their ability to increase the bioavailability of the …

Today, neurodegenerative diseases are affecting more and more individuals. A typical
therapeutic target to treat the progression of the symptoms related to these diseases is the …