Alzheimer's disease (AD) is the commonest neurodegenerative disease with slow
progression. Pieces of evidence suggest that the GABAergic system is impaired in the early …

Alzheimer's disease (AD) is a neurodegenerative disease that is characterized by
progressive memory decline and cognitive dysfunctions. Although the causes of AD have …

Neuroinflammation has been increasingly recognized to play a critical role in Alzheimer's
disease (AD). The epoxy fatty acids (EpFAs) are derivatives of the arachidonic acid …

Pupil dynamics has emerged as a critical non-invasive indicator of brain state changes. In
particular, pupillary-light-responses (PLR) in Alzheimer's disease (AD) patients show …

Macroautophagy/autophagy is the intracellular degradation process of cytoplasmic content
and damaged organelles. Autophagy is strongly associated with the progression of …

Alzheimer's disease (AD) is mainly characterized by the deposition of extracellular amyloid
plaques and intracellular accumulation of neurofibrillary tangles (NFTs). While the recent …

Alzheimer's disease and epilepsy are common nervous system diseases in older adults, and
their incidence rates tend to increase with age. Patients with mild cognitive impairment and …

Abstract Trigonelline (TGN; 1-methylpyridin-1-ium-3-carboxylate) is a widely distributed
alkaloid derived from plants. Since we previously found a neurite outgrowth effect of TGN …

Interictal spikes (IIS) are a common type of abnormal electrical activity in Alzheimer's
disease (AD) and preclinical models. The brain regions where IIS are largest are not known …

Alzheimer's disease (AD) is the most common dementia characterized by the excessive
accumulation of amyloid-beta (Aβ) and tau aggregates, as well as neuronal damage and …