Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

Daily rhythms in physiology significantly modulate drug pharmacokinetics and
pharmacodynamics according to the time-of-day, a finding that has led to the concept of …

Time-restricted feeding (TRF) is a form of intermittent fasting that involves having a longer
daily fasting period. Preliminary studies report that TRF improves cardiometabolic health in …

Microbiota-derived short-chain fatty acids (SCFAs) and organic acids produced by the
fermentation of non-digestible fibre can communicate from the microbiome to host tissues …

Circadian rhythms govern a large array of physiological and metabolic functions.
Perturbations of the daily cycle have been linked to elevated risk of developing cancer as …

Virtually every eukaryotic cell has an endogenous circadian clock and a biological sex.
These cell-based clocks have been conceptualized as oscillators whose phase can be reset …

The circadian clock system consists of a central clock located in the suprachiasmatic
nucleus in the hypothalamus and peripheral clocks in peripheral tissues. Peripheral clocks …

Breast cancer is the most common type of cancer worldwide and one of the major causes of
cancer death in women. Epidemiological studies have established a link between night-shift …

Most living beings, including humans, must adapt to rhythmically occurring daily changes in
their environment that are generated by the E arth's rotation. In the course of evolution, these …

Cold-inducible RNA-binding protein (CIRP) and RNA-binding motif protein 3 (RBM3) are
two evolutionarily conserved RNA-binding proteins that are transcriptionally upregulated in …