Oral Prevotella Species and Their Connection to Events of Clinical Relevance in Gastrointestinal and Respiratory Tracts

E Könönen, UK Gursoy - Frontiers in microbiology, 2022 - frontiersin.org
Prevotella is recognized as one of the core anaerobic genera in the oral microbiome. In
addition, members of this genus belong to microbial communities of the gastrointestinal and …

Role of the microbiota in lung cancer: insights on prevention and treatment

F Pizzo, Z Maroccia, I Hammarberg Ferri… - International Journal of …, 2022 - mdpi.com
The microbiota is increasingly recognized as a critical player in cancer onset and
progression and response to cancer chemotherapy treatment. In recent years, several …

Airway Prevotella promote TLR2-dependent neutrophil activation and rapid clearance of Streptococcus pneumoniae from the lung

KJ Horn, MA Schopper, ZG Drigot, SE Clark - Nature Communications, 2022 - nature.com
This study investigates how specific members of the lung microbiome influence the early
immune response to infection. Prevotella species are a major component of the endogenous …

The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract

O Perdijk, R Azzoni, BJ Marsland - Physiological Reviews, 2024 - journals.physiology.org
The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …

Characterization of lung and oral microbiomes in lung cancer patients using culturomics and 16S rRNA gene sequencing

Y Sun, Y Liu, J Li, Y Tan, T An, M Zhuo… - Microbiology …, 2023 - Am Soc Microbiol
Recently, microbiota dysbiosis in lung cancer has attracted immense attention. Studies on
lung microbes are mostly based on sequencing, which has left the potentially functional …

Phage therapy for pulmonary infections: lessons from clinical experiences and key considerations

G Mitropoulou, A Koutsokera, C Csajka… - European …, 2022 - Eur Respiratory Soc
Lower respiratory tract infections lead to significant morbidity and mortality. They are
increasingly caused by multidrug-resistant pathogens, notably in individuals with cystic …

The human lung microbiome—a hidden link between microbes and human health and diseases

X Yi, J Gao, Z Wang - iMeta, 2022 - Wiley Online Library
Once thought to be sterile, the human lung is now well recognized to harbor a consortium of
microorganisms collectively known as the lung microbiome. The lung microbiome is altered …

[HTML][HTML] Lung microbial-host interface through the lens of multi-omics

S Singh, JG Natalini, LN Segal - Mucosal immunology, 2022 - Elsevier
In recent years, our understanding of the microbial world within us has been revolutionized
by the use of culture-independent techniques. The use of multi-omic approaches can now …

[HTML][HTML] Insights into the role of the respiratory tract microbiome in defense against bacterial pneumonia

ZG Drigot, SE Clark - Current opinion in microbiology, 2024 - Elsevier
Highlights•Obligate anaerobes in the lung improve protection against pneumonia.•Gram-
positive bacteria in the nasal cavity correlate with reduced infection risk.•Within-genus …

[HTML][HTML] The application of multi-omics in the respiratory microbiome: Progresses, challenges and promises

J Gao, X Yi, Z Wang - Computational and Structural Biotechnology Journal, 2023 - Elsevier
The study of the respiratory microbiome has entered a multi-omic era. Through integrating
different omic data types such as metagenome, metatranscriptome, metaproteome …