The revolution in microbiota research over the past decade has provided invaluable
knowledge about the function of the microbial species that inhabit the human body. It has …

Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are
associated with systemic inflammation. Recent studies have reported stress-induced …

Cytokines, many of which signal through the JAK–STAT (Janus kinase–Signal Transducers
and Activators of Transcription) pathway, play a central role in the pathogenesis of …

Background & Aims Preclinical ulcerative colitis is poorly defined. We aimed to characterize
the preclinical systemic inflammation in ulcerative colitis, using a comprehensive set of …

Mesenchymal stem cells (MSCs) have been demonstrated to have a great potential in the
treatment of several diseases due to their differentiation and immunomodulatory capabilities …

Exosomes secreted by mesenchymal stem cells (MSCs) have shown repairing effects on
several tissue injury diseases. In this study, we aimed to investigate the effects of exosomes …

Patients with inflammatory bowel disease (IBD) suffer from depression at higher rates than
the general population. An etiological trigger of depressive symptoms is theorised to be …

Effective prevention and management of osteoporosis would require suitable methods for
population screenings and early diagnosis. Current clinically-available diagnostic methods …

Inflammation in the intestines causes abdominal pain that is challenging to manage. The
terminals of sensory neurons innervating the gut are surrounded by glia. Here, using a …

Background Colorectal cancer (CRC) and inflammatory bowel disease (IBD) are the most
prevalent diseases of the digestive system, and their association is unequivocal. A long …