Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown aetiology
affecting the colon and rectum. Multiple factors, such as genetic background, environmental …

Psoriasis is a chronic systemic inflammatory disease causing erythematosus and scaly skin
plaques; up to 30% of patients with psoriasis develop Psoriatic Arthritis (PsA), which is …

Background & Aims Intestinal fibrosis is a long-term complication in inflammatory bowel
diseases (IBD) that frequently results in functional damage, bowel obstruction, and surgery …

Summary The interleukin (IL)‐36 cytokines include 3 agonists, IL‐36α, IL‐36β, and IL‐36γ
that bind to a common receptor composed of IL‐36R and IL‐1 RA cP to stimulate …

Necrotizing enterocolitis (NEC) is a severe, currently untreatable intestinal disease that
predominantly affects preterm infants and is driven by poorly characterized inflammatory …

The skin barrier would not function without IL-1 family members, but their physiological role
in the immunological aspects of skin barrier function are often overlooked. This review …

Glioblastoma (GBM) is composed of heterogeneous tumor cell populations, including those
with stem cell properties, termed glioma stem cells (GSCs). GSCs are innately less radiation …

Interleukin (IL)-36 is a member of the IL-1 superfamily and includes three agonists (IL-36α, IL-
36β, and IL-36γ) and an antagonist (IL-36Ra). IL-36 agonists bind to heterodimeric receptor …

Interleukin-36 (IL-36) comprises to a cytokine family consisting of four isoforms IL-36α, IL-
36β, IL-36γ, and IL-36 receptor antagonist (IL-36 Ra). These IL-36 cytokines, in turn, belong …

IgE induced by type 2 immune responses in atopic dermatitis is implicated in the
progression of atopic dermatitis to other allergic diseases, including food allergies, allergic …