Skeletal muscle: A review of molecular structure and function, in health and disease

K Mukund, S Subramaniam - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …

Alpha-synuclein physiology and pathology: a perspective on cellular structures and organelles

LD Bernal-Conde, R Ramos-Acevedo… - Frontiers in …, 2020 - frontiersin.org
Alpha-synuclein (α-syn) is localized in cellular organelles of most neurons, but many of its
physiological functions are only partially understood. α-syn accumulation is associated with …

Deep learning for inferring gene relationships from single-cell expression data

Y Yuan, Z Bar-Joseph - Proceedings of the National …, 2019 - National Acad Sciences
Several methods were developed to mine gene–gene relationships from expression data.
Examples include correlation and mutual information methods for coexpression analysis …

Conceptual evolution of cell signaling

A Nair, P Chauhan, B Saha, KF Kubatzky - International journal of …, 2019 - mdpi.com
During the last 100 years, cell signaling has evolved into a common mechanism for most
physiological processes across systems. Although the majority of cell signaling principles …

[HTML][HTML] Neuronal mechanisms underlying opioid-induced respiratory depression: our current understanding

JM Ramirez, NJ Burgraff, AD Wei… - Journal of …, 2021 - journals.physiology.org
Opioid-induced respiratory depression (OIRD) represents the primary cause of death
associated with therapeutic and recreational opioid use. Within the United States, the rate of …

Signalling dynamics in embryonic development

KF Sonnen, CY Janda - Biochemical Journal, 2021 - portlandpress.com
In multicellular organisms, cellular behaviour is tightly regulated to allow proper embryonic
development and maintenance of adult tissue. A critical component in this control is the …

Interleukin‐1α and tumor necrosis factor α as an inducer for reactive‐oxygen‐species‐mediated NOD‐like receptor protein 1/NOD‐like receptor protein 3 …

Z Aghelan, S Karima, H Khazaie… - European journal of …, 2022 - Wiley Online Library
Background and purpose There is some evidence that cytokines may play an important role
in sleep deprivation; however, the underlying mechanisms are still unknown. So, the present …

Entire expressed peripheral blood transcriptome in pediatric severe malarial anemia

SB Anyona, Q Cheng, SA Wasena, SW Osata… - Nature …, 2024 - nature.com
This study on severe malarial anemia (SMA: Hb< 6.0 g/dL), a leading global cause of
childhood morbidity and mortality, compares the entire expressed whole blood host …

Structural Characterization of Polysaccharide Derived from Gastrodia elata and Its Immunostimulatory Effect on RAW264.7 Cells

H Guan, X Ling, J Xu, Y Zhu, J Zhang, X Liu - Molecules, 2022 - mdpi.com
A polysaccharide from Gastrodia elata (named GEP-1) was isolated with a DEAE-52 column
and Sephadex G-100 column. The structural characteristics showed that GEP-1 was mainly …

A review on anticancer profile of flavonoids: Sources, chemistry, mechanisms, structure-activity relationship and anticancer activity

S Shah, R Narang, VJ Singh, G Pilli… - … Formerly: Current Drug …, 2023 - ingentaconnect.com
Background: Epidemiological studies have suggested that a regular intake of flavonoids is
beneficial for cellular homeostasis and in the prevention of the transformation of normal cells …