Oxidative stress and protein modifications are frequently observed in numerous disease
states. Glucose constitutes a vital nutrient necessary to cellular oxygen metabolism …

Albumin, a major transporting protein in the blood, is the main target of modification that
affects the binding of drugs to Sudlow's site I and II. These modification of serum protein …

We present the first demonstration of glycated albumin detection and quantification using
Raman spectroscopy without the addition of reagents. Glycated albumin is an important …

Diamond-like carbon (DLC) coatings are extremely useful for creating biocompatible
surfaces on medical implants. DLC and silicon doped DLC synthesised on silicon wafer …

In vivo modification of proteins by molecules with reactive carbonyl groups leads to
intermediate and advanced glycation end products (AGE). Glucose is a significant glycation …

The interaction between serum albumin (SA) and drugs has provided an interesting ground
for understanding of drug effects, especially in drug distribution and drug–drug interaction …

This report used high-performance affinity microcolumns to examine the changes in binding
by sulfonylurea drugs to in vivo glycated HSA that had been isolated from individual patients …

This study compared a hydroxyl radical-generating system (HRGS)(0.05–0.2 mM Fe 3++ 0.6
mM H 2 O 2) and a glycation system (GLY)(0.05–0.2 mM Fe 3++ 0.05 M glucose) for their …

Understanding the molecular basis of the disease is of the utmost scientific interest as it
contributes to the development of targeted strategies of prevention, diagnosis, and therapy …

Garlic has been reported to inhibit protein glycation, a process that underlies several
disease processes, including chronic complications of diabetes mellitus. Biophysical …